Background Both cocaine use and strokes impact public health. Cocaine is a putative cause
of strokes, but no systematic review of the scientific evidence has been published. Methods …

Objective In this systematic review and meta-analysis of psoriatic arthritis (PsA) studies, we
pooled data from existing literature to (1) estimate the prevalence of mental health disorders …

Objective This paper describes the University of Michigan's nine-year experience in
developing and using a full-text search engine designed to facilitate information retrieval (IR) …

Background: Understanding the relationship between alcohol abuse, a common and
theoretically modifiable condition, and the most common cause of death in the world …

Background HIV infected (HIV+) individuals may be more susceptible to alcohol-related
harm than uninfected individuals. Methods We analyzed data on HIV+ and uninfected …

Background: Although cannabis is known to have cardiovascular and psychoactive effects,
the implications of its use before surgery are currently unknown. The objective of the present …

Background & Aims Population-level evidence for the impact of direct-acting antiviral (DAA)
therapy on hepatitis C virus (HCV)-related disease burden is lacking. We aimed to evaluate …

Background Treatment for opioid use disorder is important because of the negative health,
societal and economic consequences of illicit opioid use, but treatment adherence can be a …

Background: Multimorbidity (the presence of multiple chronic conditions) is associated with
high levels of healthcare utilization and associated costs. We investigated the association …

BackgroundThe association between physical disorders and suicide remains unclear. The
aim of this study was to examine the relationship between physical disorders and suicide …