Research should equitably reflect responses in men and women. Including women in
research, however, necessitates an understanding of the ovarian hormones and menstrual …

Impaired circulating estrogen levels have been related to impaired glycemic homeostasis
and diabetes mellitus (DM), both in females and males. However, for the last twenty years …

The solute carrier family 2 facilitated glucose transporter member 4 (GLUT4) plays a key role
in the insulin‐induced glucose uptake by muscle and adipose tissues. In prediabetes and …

Vascular endothelial growth factor A (VEGFA) is a key factor in the regulation of
angiogenesis in adipose tissue. Poor vascularization during adipose tissue proliferation …

Aims/hypothesis The discovery of osteocalcin, a protein synthetized by osteoblasts, as a
hormone that has positive effects on insulin resistance, contributed to support the concept of …

Inhibins are gonadal glycoprotein hormones whose main endocrine function is to inhibit
pituitary FSH secretion. In addition to testes and ovaries, other steroid-producing organs are …

The ability of adipose tissue to expand is dependent on adipocyte differentiation and
adipose tissue glucose disposal. The CCAAT/enhancer-binding protein alpha (CEBPA) …

Previous studies have reported the anti-obesity effects of α, β-Amyrin in high fat-fed mice.
This study aimed to evaluate whether α, β-Amyrin has an anti-adipogenic effect in 3T3-L1 …

Type 2 diabetes (T2D) is a worldwide health problem, ranked as one of the leading causes
for severe morbidity and premature mortality in modern society. Management of blood …

Background: Estrogens are involved in glycemic regulation, playing an important role in the
development and/or progression of insulin resistance. For that, estrogens regulate the …