Nonalcoholic steatohepatitis-related hepatocellular carcinoma: pathogenesis and treatment
Nonalcoholic fatty liver disease (NAFLD), including its more severe manifestation,
nonalcoholic steatohepatitis (NASH), has a global prevalence of 20–25% and is a major …
nonalcoholic steatohepatitis (NASH), has a global prevalence of 20–25% and is a major …
From NASH to HCC: current concepts and future challenges
Caloric excess and sedentary lifestyle have led to a global epidemic of obesity and
metabolic syndrome. The hepatic consequence of metabolic syndrome and obesity …
metabolic syndrome. The hepatic consequence of metabolic syndrome and obesity …
[HTML][HTML] Apoptosis and non-alcoholic fatty liver diseases
T Kanda, S Matsuoka, M Yamazaki… - World journal of …, 2018 - ncbi.nlm.nih.gov
The number of patients with nonalcoholic fatty liver diseases (NAFLD) including
nonalcoholic steatohepatitis (NASH), has been increasing. NASH causes cirrhosis and …
nonalcoholic steatohepatitis (NASH), has been increasing. NASH causes cirrhosis and …
[PDF][PDF] The role of senescence in the development of nonalcoholic fatty liver disease and progression to nonalcoholic steatohepatitis
AM Papatheodoridi, L Chrysavgis, M Koutsilieris… - …, 2020 - Wiley Online Library
In recent years, cellular senescence has generated a lot of interest among researchers
because of its involvement in both the normal aging process and common human diseases …
because of its involvement in both the normal aging process and common human diseases …
Role of ceramidases in sphingolipid metabolism and human diseases
Human pathologies such as Alzheimer's disease, type 2 diabetes-induced insulin
resistance, cancer, and cardiovascular diseases have altered lipid homeostasis. Among …
resistance, cancer, and cardiovascular diseases have altered lipid homeostasis. Among …
Frequently mutated genes/pathways and genomic instability as prevention targets in liver cancer
The incidence of liver cancer has increased in recent years. Worldwide, liver cancer is
common: more than 600000 related deaths are estimated each year. In the USA, about …
common: more than 600000 related deaths are estimated each year. In the USA, about …
Non-alcoholic fatty liver disease induces signs of Alzheimer's disease (AD) in wild-type mice and accelerates pathological signs of AD in an AD model
DG Kim, A Krenz, LE Toussaint, KJ Maurer… - Journal of …, 2016 - Springer
Background Non-alcoholic fatty liver disease (NAFLD) is a chronic liver disease afflicting
about one third of the world's population and 30% of the US population. It is induced by …
about one third of the world's population and 30% of the US population. It is induced by …
MAFLD: an optimal framework for understanding liver cancer phenotypes
Hepatocellular carcinoma has a substantial global mortality burden which is rising despite
advancements in tackling the traditional viral risk factors. Metabolic (dysfunction) associated …
advancements in tackling the traditional viral risk factors. Metabolic (dysfunction) associated …
Inhibiting xCT/SLC7A11 induces ferroptosis of myofibroblastic hepatic stellate cells but exacerbates chronic liver injury
Abstract Background & Aims The outcome of liver injury is dictated by factors that control the
accumulation of myofibroblastic (activated) hepatic stellate cells (MF‐HSCs) but therapies …
accumulation of myofibroblastic (activated) hepatic stellate cells (MF‐HSCs) but therapies …
Non-Alcoholic Fatty Liver Disease Is Associated with a Decreased Catalase (CAT) Level, CT Genotypes and the T Allele of the -262 C/T CAT Polymorphism
M Kosmalski, I Szymczak-Pajor, J Drzewoski… - Cells, 2023 - mdpi.com
Background: It is well known that oxidative stress plays an important role in the development
of non-alcoholic fatty liver disease (NAFLD). It has been suggested that an insufficient …
of non-alcoholic fatty liver disease (NAFLD). It has been suggested that an insufficient …