Adipokines are cell-signaling proteins secreted by adipose tissue that has been related to a
low-grade state of inflammation and different pathologies. The present review aims to …

The rates of obesity and diabetes are increasing worldwide, whereas the age of onset for
both obesity and diabetes are decreasing steadily. Obesity and diabetes are associated with …

Breast cancer (BC) is a malignant breast tumor confronted with high invasion, metastasis
and recurrence rate, and adipocytes are the largest components in breast tissue. The …

Insulin resistance (IR) is a condition which refers to individuals whose cells and tissues
become insensitive to the peptide hormone, insulin. Over the recent years, a wealth of data …

During the last decades, research on adipose tissues has spread in parallel with the
extension of obesity. Several observations converged on the idea that adipose tissues are …

Adipocytes account for the largest proportion among the cells that comprise breast tissue;
therefore, they are considered to be a critical cell type in the tumor microenvironment of …

Resistin, a small secretory molecule, has been implicated to play an important role in the
development of insulin resistance under obese condition. For the past few decades, it has …

Adipocytes are a type of stromal cell found in numerous different tissues that serve an active
role in the tumor microenvironment. Cancer‑associated adipocytes (CAAs) display a …

Purpose The current review shows evidence for the role of adipokines in breast cancer (BC)
pathogenesis summarizing the mechanisms underlying the association between adipokines …

Growing evidence indicates that resistin—an obesity-related cytokine—is upregulated in
breast cancer patients, yet its impact on breast cancer behavior remains to be ascertained …