[HTML][HTML] Cardiac toxicity associated with immune checkpoint inhibitors: a systematic review

W Shalata, A Abu-Salman, R Steckbeck… - Cancers, 2021 - mdpi.com
Simple Summary This review article addresses the toxic effects on the heart associated with
the use of certain cancer-treating drugs known as immune checkpoint inhibitors. These …

Cardiovascular complications of immune checkpoint inhibitors for cancer

F Thuny, J Naidoo, TG Neilan - European heart journal, 2022 - academic.oup.com
Over the last decade or so, there has been a paradigm shift in the oncologic care of patients
with a range of solid tumour and haematologic malignancies, away from traditional cytotoxic …

2022 ESC Guidelines on cardio-oncology developed in collaboration with the European Hematology Association (EHA), the European Society for Therapeutic …

AR Lyon, T López-Fernández, LS Couch… - European Heart …, 2022 - academic.oup.com
ESC Guidelines e341 (1) the specific situation of the patient. In this respect, it is specified
that, unless otherwise provided for by national regulations, offlabel use of medication should …

Atherosclerosis With Immune Checkpoint Inhibitor Therapy: Evidence, Diagnosis, and Management: JACC: CardioOncology State-of-the-Art Review

GA Suero-Abreu, MV Zanni, TG Neilan - Cardio Oncology, 2022 - jacc.org
As the clinical applications of immune checkpoint inhibitors (ICIs) expand, our knowledge of
the potential adverse effects of these drugs continues to broaden. Emerging evidence …

[HTML][HTML] Risk Factors for Immune Checkpoint Inhibitor–Mediated Cardiovascular Toxicities

LI Yousif, EM Screever, D Versluis… - Current Oncology …, 2023 - Springer
Abstract Purpose of Review Immune checkpoint inhibitors (ICIs) have improved the field of
cancer, especially in patients with advanced malignancies. Nevertheless, cardiovascular …

The incidence and risk of cardiovascular events associated with immune checkpoint inhibitors in Asian populations

CH Chiang, CH Chiang, KSK Ma… - Japanese Journal of …, 2022 - academic.oup.com
Objectives Immune checkpoint inhibitors are associated with adverse cardiovascular events.
However, there are no data characterizing cardiovascular events among Asians on immune …

Mediators and mechanisms of immune checkpoint inhibitor‐associated myocarditis: Insights from mouse and human

J Gong, TG Neilan, DA Zlotoff - Immunological Reviews, 2023 - Wiley Online Library
The broad application of immune checkpoint inhibitors (ICIs) has led to significant gains in
cancer outcomes. By abrogating inhibitory signals, ICIs promote T cell targeting of cancer …

Cardiovascular toxicity and risk mitigation with lung cancer treatment

N Yegya-Raman, E Berlin, SJ Feigenberg, B Ky… - Current Oncology …, 2023 - Springer
Abstract Purpose of Review Patients with lung cancer often have concomitant
cardiovascular comorbidities and receive potentially cardiotoxic therapies. As oncologic …

Immune checkpoint inhibitors–the revolutionary cancer immunotherapy comes with a cardiotoxic price

A Achim, K Liblik, S Gevaert - Trends in Cardiovascular Medicine, 2022 - Elsevier
The development of immune checkpoint inhibitors (ICIs) has provided a novel and
revolutionary treatment option for previously incurable cancers. However, this major …

[HTML][HTML] Immune checkpoint inhibitors break whose heart? Perspectives from cardio-immuno-oncology

Y He, H Yu, S Dai, M He, L Ma, Z Xu, F Luo, L Wang - Genes & Diseases, 2024 - Elsevier
Immune checkpoint inhibitors (ICIs) are monoclonal antibody antagonists, which can block
cytotoxic T lymphocyte antigen-4 (CTLA-4), programmed death-1/ligand-1 (PD-1/PD-L1) …