Plant phenolics are considered to be a vital human dietary component and exhibit a
tremendous antioxidant activity as well as other health benefits. Epidemiology evidence …

The dermis is primarily composed of the extracellular matrix (ECM) and fibroblasts. During
the aging process, the dermis undergoes significant changes. Collagen, which is a major …

Skin is the largest and most complex organ in the human body comprised of multiple layers
with different types of cells. Different kinds of environmental stressors, for example …

Background: Quercetin, a major flavonol, wildly exists in plantage, which has been reported
to have an anti-apoptosis and anti-inflammation effects on vascular endothelial cells, but its …

Matrix metalloproteinases (MMPs) are zinc-containing endopeptidases with an extensive
range of substrate specificities. Collectively, these enzymes are able to degrade various …

Pathological pain can be initiated after inflammation and/or peripheral nerve injury. It is a
consequence of the pathological functioning of the nervous system rather than only a …

Exposure to UV light triggers the rapid generation and accumulation of reactive oxygen
species (ROS) in skin cells, with consequent increase in oxidative stress and thus in …

The physiological functions and bioavailability of flavonoids have been widely investigated
since their bioactivities were identified about 80 years ago. Quercetin is a typical flavonoid …

Skin aging is associated with the accumulation of senescent cells and is related to many
pathological changes, including decreased protection against pathogens, increased …

Background Quercetin is one of the most critical endogenous anti-oxidants used widely in
cosmetics, nutraceuticals, and pharmaceuticals products for skincare and therapeutics due …