DNA microarrays: a powerful genomic tool for biomedical and clinical research
V Trevino, F Falciani, HA Barrera-Saldaña - Molecular medicine, 2007 - Springer
Among the many benefits of the Human Genome Project are new and powerful tools such as
the genome-wide hybridization devices referred to as microarrays. Initially designed to …
the genome-wide hybridization devices referred to as microarrays. Initially designed to …
Network pharmacology studies on the bioactive compounds and action mechanisms of natural products for the treatment of diabetes mellitus: a review
Diabetes mellitus (DM) is a kind of chronic and metabolic disease, which can cause a
number of diseases and severe complications. Network pharmacology approach is …
number of diseases and severe complications. Network pharmacology approach is …
Human protein reference database—2009 update
Abstract Human Protein Reference Database (HPRD—http://www. hprd. org/), initially
described in 2003, is a database of curated proteomic information pertaining to human …
described in 2003, is a database of curated proteomic information pertaining to human …
[HTML][HTML] Human protein reference database—2009 update
TSK Prasad, R Goel, K Kandasamy… - Nucleic acids …, 2009 - ncbi.nlm.nih.gov
Abstract Human Protein Reference Database (HPRD—http://www. hprd. org/), initially
described in 2003, is a database of curated proteomic information pertaining to human …
described in 2003, is a database of curated proteomic information pertaining to human …
Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes
JA Todd, NM Walker, JD Cooper, DJ Smyth… - Nature …, 2007 - nature.com
Abstract The Wellcome Trust Case Control Consortium (WTCCC) primary genome-wide
association (GWA) scan on seven diseases, including the multifactorial autoimmune disease …
association (GWA) scan on seven diseases, including the multifactorial autoimmune disease …
IthaGenes: an interactive database for haemoglobin variations and epidemiology
Inherited haemoglobinopathies are the most common monogenic diseases, with millions of
carriers and patients worldwide. At present, we know several hundred disease-causing …
carriers and patients worldwide. At present, we know several hundred disease-causing …
Evaluating the heritability explained by known susceptibility variants: a survey of ten complex diseases
Recently, an increasing number of susceptibility variants have been identified for complex
diseases. At the same time, the concern of “missing heritability” has also emerged. There is …
diseases. At the same time, the concern of “missing heritability” has also emerged. There is …
Human Protein Reference Database and Human Proteinpedia as discovery tools for systems biology
Although high-throughput technologies used in biology have resulted in the accumulation of
vast amounts of data in the literature, it is becoming difficult for individual investigators to …
vast amounts of data in the literature, it is becoming difficult for individual investigators to …
PTPN2, a candidate gene for type 1 diabetes, modulates interferon-γ–induced pancreatic β-cell apoptosis
F Moore, ML Colli, M Cnop, MI Esteve, AK Cardozo… - Diabetes, 2009 - Am Diabetes Assoc
OBJECTIVE The pathogenesis of type 1 diabetes has a strong genetic component. Genome-
wide association scans recently identified novel susceptibility genes including the …
wide association scans recently identified novel susceptibility genes including the …
Confirmation of HLA class II independent type 1 diabetes associations in the major histocompatibility complex including HLA‐B and HLA‐A
JMM Howson, NM Walker, D Clayton… - Diabetes, Obesity …, 2009 - Wiley Online Library
Aim: Until recently, human leucocyte antigen (HLA) class II‐independent associations with
type 1 diabetes (T1D) in the Major Histocompatibility Complex (MHC) region were not …
type 1 diabetes (T1D) in the Major Histocompatibility Complex (MHC) region were not …