[HTML][HTML] Polymer-and lipid-based nanocarriers for ocular drug delivery: current status and future perspectives

H Han, S Li, M Xu, Y Zhong, W Fan, J Xu, T Zhou… - Advanced Drug Delivery …, 2023 - Elsevier
Ocular diseases seriously affect patients' vision and life quality, with a global morbidity of
over 43 million blindness. However, efficient drug delivery to treat ocular diseases …

[HTML][HTML] Nanotechnology based drug delivery systems for the treatment of anterior segment eye diseases

AL Onugwu, CS Nwagwu, OS Onugwu… - Journal of Controlled …, 2023 - Elsevier
Diseases affecting the anterior segment of the eye are the primary causes of vision
impairment and blindness globally. Drug administration through the topical ocular route is …

Infectious keratitis: an update on epidemiology, causative microorganisms, risk factors, and antimicrobial resistance

DSJ Ting, CS Ho, R Deshmukh, DG Said, HS Dua - Eye, 2021 - nature.com
Corneal opacity is the 5th leading cause of blindness and visual impairment globally,
affecting~ 6 million of the world population. In addition, it is responsible for 1.5–2.0 million …

siRNA: Mechanism of action, challenges, and therapeutic approaches

W Alshaer, H Zureigat, A Al Karaki, A Al-Kadash… - European journal of …, 2021 - Elsevier
Owing to specific and compelling gene silencing, RNA interference (RNAi) is expected to
become an essential approach in treating a variety of infectious, hemato-oncological …

Defining dry eye from a clinical perspective

K Tsubota, SC Pflugfelder, Z Liu, C Baudouin… - International journal of …, 2020 - mdpi.com
Over the past decades, the number of patients with dry eye disease (DED) has increased
dramatically. The incidence of DED is higher in Asia than in Europe and North America …

Tfos dews ii epidemiology report

F Stapleton, M Alves, VY Bunya, I Jalbert, K Lekhanont… - The ocular …, 2017 - Elsevier
The subcommittee reviewed the prevalence, incidence, risk factors, natural history, morbidity
and questionnaires reported in epidemiological studies of dry eye disease (DED). A meta …

TFOS DEWS II diagnostic methodology report

JS Wolffsohn, R Arita, R Chalmers, A Djalilian… - The ocular …, 2017 - Elsevier
The role of the Tear Film and Ocular Surface Society (TFOS) Dry Eye Workshop (DEWS) II
Diagnostic Methodology Subcommittee was 1) to identify tests used to diagnose and monitor …

TFOS DEWS II management and therapy report

L Jones, LE Downie, D Korb, JM Benitez-del-Castillo… - The ocular …, 2017 - Elsevier
The members of the Management and Therapy Subcommittee undertook an evidence-
based review of current dry eye therapies and management options. Management options …

Tfos dews ii pathophysiology report

AJ Bron, CS de Paiva, SK Chauhan, S Bonini… - The ocular …, 2017 - Elsevier
Abstract The TFOS DEWS II Pathophysiology Subcommittee reviewed the mechanisms
involved in the initiation and perpetuation of dry eye disease. Its central mechanism is …

TFOS DEWS II report executive summary

JP Craig, JD Nelson, DT Azar, C Belmonte, AJ Bron… - The ocular …, 2017 - Elsevier
This article presents an Executive Summary of the conclusions and recommendations of the
10-chapter TFOS DEWS II report. The entire TFOS DEWS II report was published in the July …