Invasive candidiasis in critical care: challenges and future directions

C Logan, I Martin-Loeches, T Bicanic - Intensive care medicine, 2020 - Springer
Invasive candidiasis is the most common critical care-associated fungal infection with a
crude mortality of~ 40–55%. Important factors contributing to risk of invasive candidiasis in …

Intensive care medicine research agenda on invasive fungal infection in critically ill patients

M Bassetti, J Garnacho-Montero, T Calandra… - Intensive care …, 2017 - Springer
Purpose To describe concisely the current standards of care, major recent advances,
common beliefs that have been contradicted by recent trials, areas of uncertainty, and …

Specificity Influences in (1→3)-β-d-Glucan-Supported Diagnosis of Invasive Fungal Disease

MA Finkelman - Journal of Fungi, 2020 - mdpi.com
(1→ 3)-β-glucan (BDG) testing as an adjunct in the diagnosis of invasive fungal disease
(IFD) has been in use for nearly three decades. While BDG has a very high negative …

Recent advances in the molecular diagnosis of mucormycosis

SS Dadwal, DP Kontoyiannis - Expert review of molecular …, 2018 - Taylor & Francis
Introduction: Fungal infection burden related to Mucorales has been on the rise with
significant associated morbidity and mortality. The major obstacle in the management has …

Performance of the beta-glucan test for the diagnosis of invasive fusariosis and scedosporiosis: a meta-analysis

F Lamoth, M Nucci, A Fernandez-Cruz… - Medical …, 2023 - academic.oup.com
Abstract The (1→ 3)-β-D-glucan (BDG) is a component of the fungal cell wall that can be
detected in serum and used as an adjunctive tool for the diagnosis of invasive mold …

Mucormycosis and COVID-19-associated mucormycosis: insights of a deadly but neglected mycosis

LC García-Carnero, HM Mora-Montes - Journal of Fungi, 2022 - mdpi.com
The ongoing COVID-19 pandemic has quickly become a health threat worldwide, with high
mortality and morbidity among patients with comorbidities. This viral infection promotes the …

Polysaccharides cell wall architecture of mucorales

K Lecointe, M Cornu, J Leroy, P Coulon… - Frontiers in …, 2019 - frontiersin.org
Invasive fungal infections are some of the most life-threatening infectious diseases in the
hospital setting. In industrialized countries, the most common fungal species isolated from …

Why are so many cases of invasive aspergillosis missed?

F Danion, C Rouzaud, A Duréault, S Poirée… - Medical …, 2019 - academic.oup.com
Invasive aspergillosis (IA) incidence is increasing in several countries like France, and
numerous cases are indeed missed and still only diagnosed at autopsy as evidenced by …

Emerging invasive fungal infections: clinical features and controversies in diagnosis and treatment processes

H Zhang, A Zhu - Infection and Drug Resistance, 2020 - Taylor & Francis
Background The diagnosis and treatment of invasive fungal infection (IFI) are still
challenging due to its complexity and non-specificity. This study was aimed to investigate the …

T2 magnetic resonance assay: overview of available data and clinical implications

IM Zacharioudakis, FN Zervou, E Mylonakis - Journal of fungi, 2018 - mdpi.com
Invasive candidiasis is a common healthcare-associated infection with a high mortality rate
that can exceed 60% in cases of septic shock. Blood culture performance is far from ideal …