The process of aging includes changes in cellular biology that affect local interactions
between cells and their environments and eventually propagate to systemic levels. In the …

There is increasing interest in factors that may modulate white matter (WM) breakdown and,
consequentially, age-related cognitive and behavioral deficits. Recent diffusion tensor …

Importance Little is known about the associations of strict blood pressure (BP) control with
microstructural changes in small vessel disease markers. Objective To investigate the …

Recent reports suggest declines in the age-specific risk of Alzheimer's dementia in higher
income Western countries. At the same time, investigators believe that worldwide trends of …

BACKGROUND: It is unknown whether hypertension plays any role in cerebral myelination.
To fill this knowledge gap, we studied 90 cognitively unimpaired adults, age range 40 to 94 …

Chronic hypertension, or high blood pressure, is the most prevalent vascular risk factor that
accelerates cognitive aging and increases risk for Alzheimer's disease and related …

Background and purpose Cerebral small vessel disease (CSVD) is a common cause of
stroke and senile vascular cognitive impairment, imposing a heavy burden on public health …

The influence of hypertension and aging alone on brain structure has been described
extensively. Our understanding of the interaction of hypertension with aging to brain …

Background Hypertension-related illnesses are a leading cause of disability and death in
the United States, where hypertension prevalence in adults is 46%, with only half of those …

Background/Objective This study aimed to evaluate serum neurofilament light chain (NF‐L)
levels in former professional contact sports athletes with multiple concussions (ExPro) as a …