Peptides are biopolymers, typically consisting of 2–50 amino acids. They are biologically
produced by the cellular ribosomal machinery or by non-ribosomal enzymes and …

Technological advances enabling massively parallel measurement of biological features—
such as microarrays, high-throughput sequencing and mass spectrometry—have ushered in …

The advent of proteomics offers an unprecedented opportunity to predict dementia onset.
We examined this in data from 52,645 adults without dementia in the UK Biobank, with 1,417 …

The prevalence of many chronic diseases has increased over the last decades. It has been
postulated that dysbiosis driven by environmental factors such as antibiotic use is shifting …

Gene set enrichment analysis has become one of the most frequently used applications in
molecular biology research. Originally developed for gene sets, the same statistical …

Ethiopian mustard (Brassica carinata) in the Brassicaceae family possesses many excellent
agronomic traits. Here, the high-quality genome sequence of B. carinata is reported …

Scientists from nearly all disciplines face the problem of simultaneously evaluating many
hypotheses. Conducting multiple comparisons increases the likelihood that a non-negligible …

In computational biology and other sciences, researchers are frequently faced with a choice
between several computational methods for performing data analyses. Benchmarking …

Importance Certain psychiatric and immune-related disorders are reciprocal risk factors.
However, the nature of these associations is unclear. Objective To characterize the …

Motivation Although gene set enrichment analysis has become an integral part of high-
throughput gene expression data analysis, the assessment of enrichment methods remains …