The self-organized structure of glioma oncostreams and the disruptive role of passive cells
Oncostreams are self-organized structures formed by spindle-like, elongated, self-propelled
cells recently described in glioblastomas and especially in gliosarcomas. Cells within these …
cells recently described in glioblastomas and especially in gliosarcomas. Cells within these …
Spatiotemporal heterogeneity in CNS tumors
Central nervous system (CNS) tumors, particularly gliomas such as glioblastoma (GBM),
have the worst prognosis. The median survival time was only 14–16 months. This is largely …
have the worst prognosis. The median survival time was only 14–16 months. This is largely …
Glioblastoma invasion relies on actomyosin contractility and metalloproteinase activity
Glioblastoma multiforme (GBM) is one of the most aggressive and invasive types of brain
tumors with a 5-year survival rate of less than 20%. Due to its highly invasive phenotype …
tumors with a 5-year survival rate of less than 20%. Due to its highly invasive phenotype …