Curcumin and its derivatives in cancer therapy: Potentiating antitumor activity of cisplatin and reducing side effects

AJ Abadi, S Mirzaei, MK Mahabady… - Phytotherapy …, 2022 - Wiley Online Library
Curcumin is a phytochemical isolated from Curcuma longa with potent tumor‐suppressor
activity, which has shown significant efficacy in pre‐clinical and clinical studies. Curcumin …

Anticancer drug-induced cardiotoxicity: insights and pharmacogenetics

A Adhikari, SMB Asdaq, MA Al Hawaj, M Chakraborty… - Pharmaceuticals, 2021 - mdpi.com
The advancement in therapy has provided a dramatic improvement in the rate of recovery
among cancer patients. However, this improved survival is also associated with enhanced …

Icariin exhibits protective effects on cisplatin-induced cardiotoxicity via ROS-mediated oxidative stress injury in vivo and in vitro

J Xia, J Hu, R Zhang, W Liu, H Zhang, Z Wang, S Jiang… - Phytomedicine, 2022 - Elsevier
Background Cisplatin-induced cardiotoxicity severely limits its clinical application as an
antitumor drug and increases the risk of cardiovascular disease. Icariin (ICA), the main …

[PDF][PDF] Ameliorating effect of lycopene and N-acetylcysteine against cisplatin-induced cardiac injury in rats

A Elsayed, A Elkomy, M Alkafafy, R Elkammar, SE Fadl… - Pak Vet J, 2022 - researchgate.net
Cisplatin (CP) is used to treat a wide range of tumors and kills cells (anti-neoplastic drug)
through different mechanisms, including, formation of reactive oxygen species (ROS), DNA …

Redox interactions-induced cardiac toxicity in cancer therapy

X Fu, J Tang, P Wen, Z Huang, M Najafi - Archives of biochemistry and …, 2021 - Elsevier
Cancer patients undergoing radiotherapy, chemotherapy, or targeted cancer therapy are
exposed to the risk of several side effects because of the heavy production of ROS by …

[HTML][HTML] Breast cancer and the cardiovascular disease: a narrative review

SP Cherukuri, R Chikatimalla, T Dasaradhan, J Koneti… - Cureus, 2022 - ncbi.nlm.nih.gov
Breast cancer is the most common malignancy affecting females worldwide and is also
among the top causes of all cancer-related deaths. Cardiovascular disease (CVD) is known …

Clinical significance of carnitine in the treatment of cancer: from traffic to the regulation

R Farahzadi, MS Hejazi, O Molavi… - Oxidative Medicine …, 2023 - Wiley Online Library
Metabolic reprogramming is a common hallmark of cancer cells. Cancer cells exhibit
metabolic flexibility to maintain high proliferation and survival rates. In other words …

The role of nutrition in primary and secondary prevention of cardiovascular damage in childhood cancer survivors

F Guida, R Masetti, L Andreozzi, D Zama, M Fabi… - Nutrients, 2022 - mdpi.com
Innovative therapeutic strategies in childhood cancer led to a significant reduction in cancer-
related mortality. Cancer survivors are a growing fragile population, at risk of long-term side …

Breast milk mesenchymal stem cells abate cisplatin-induced cardiotoxicity in adult male albino rats via modulating the AMPK pathway

MM Nageeb, SF Saadawy, SH Attia - Scientific Reports, 2022 - nature.com
Myocardial injury influenced by cisplatin (Cis) is a compelling reason to hunt out a treatment
modality to overcome such a threat in cisplatin-treated patients. Breast Milk mesenchymal …

Acetyl-L-Carnitine and Liposomal Co-Enzyme Q10 Attenuate Hepatic Inflammation, Apoptosis, and Fibrosis Induced by Propionic Acid

AM Alhusaini, R Alsoghayer, L Alhushan… - International Journal of …, 2023 - mdpi.com
Propionic acid (PRA) is a metabolic end-product of enteric bacteria in the gut, and it is
commonly used as a food preservative. Despite the necessity of PRA for immunity in the …