Cancer is one of the most fatal diseases of recent times that causes several deaths every
year. The disease variations in different parts of the world, the impact of available medical …

Breast cancer is the leading cause of cancer-related fatalities in female worldwide. Effective
therapies with low side effects for breast cancer treatment and prevention are, accordingly …

A proposed strategy to overcome multidrug resistance (MDR) of anticancer drugs in
chemotherapy is to disable the efflux function of P-glycoprotein (P-gp). In this study, based …

Breast cancer is the first malignant tumor in women, and its incidence is also increasing year
by year. Chemotherapy is one of the standard therapies for breast cancer, but the resistance …

A series of cyclic peptides,[(DipR)(WR) 4],[(DipR) 2 (WR) 3],[(DipR) 3 (WR) 2],[(DipR) 4
(WR)], and [DipR] 5, and their linear counterparts containing arginine (R) as positively …

Numerous nanocarriers have been developed to deliver drugs for the treatment of
hepatocellular carcinoma. However, the lack of specific targeting ability, the low …

Aim: The authors aimed to develop Dox@ Rg1 nanoparticles with decreased cardiotoxicity
to expand their application in cancer. Materials & methods: Dox@ Rg1 nanoparticles were …

Purpose This study aimed to construct a DOX conjugate with liver tumor targeting and acid
sensitivity based on a short aromatic peptide FFYEE, which could amplify the tumor …

Cell-impermeable and negatively charged compounds' cellular uptake across the cell
membranes remains challenging. Herein, the synthesis of four linear [(WWRR) 2,(WWRR) …

RNA interference (RNAi) is a powerful tool capable of targeting virtually any protein without
time-consuming and expensive drug development studies. However, due to obstacles facing …