The IL-2A receptor pathway and its role in lymphocyte differentiation and function

Y Li, X Li, X Geng, H Zhao - Cytokine & growth factor reviews, 2022 - Elsevier
Murine myeloid cells are developed from hemopoietic stem/progenitor cells. Different types
of progenitor cells have variable differentiation potentials. Among the ten main types of cells …

Selective glomerular hypofiltration syndrome

B Quiroga, A Ortiz, J Díez - Nephrology Dialysis Transplantation, 2024 - academic.oup.com
The estimated glomerular filtration rate (eGFR) provides insight into cardiovascular disease
(CVD) risk stratification and proactive management. Accumulating evidence suggests that …

[HTML][HTML] Inflammation and heart failure: a two-sample Mendelian randomization study

S Remmelzwaal, S van Oort, ML Handoko… - Journal of …, 2022 - journals.lww.com
Background It is hypothesized that inflammation leads to heart failure. Results from
observational studies thus far have been inconsistent and it is unclear whether inflammation …

Soluble TNFR1 has greater reproducibility than IL-6 for the assessment of chronic inflammation in older adults: the case for a new inflammatory marker in aging

T Laskow, J Langdon, S Sepehri, M Davalos-Bichara… - GeroScience, 2024 - Springer
Chronic inflammatory pathway activation, commonly referred to as “Inflammaging” or chronic
inflammation (CI), is associated with frailty, cognitive and functional decline, and other …

Ca2+ mishandling in heart failure: Potential targets

A Val‐Blasco, M Gil‐Fernández, A Rueda… - Acta …, 2021 - Wiley Online Library
Ca2+ mishandling is a common feature in several cardiovascular diseases such as heart
failure (HF). In many cases, impairment of key players in intracellular Ca2+ homeostasis has …

Soluble interleukin-2 receptor combined with interleukin-8 is a powerful predictor of future adverse cardiovascular events in patients with acute myocardial infarction

K Pan, C Xu, C Chen, S Chen, Y Zhang… - Frontiers in …, 2023 - frontiersin.org
Background Little is known about the role of interleukin (IL) in patients with acute myocardial
infarction (MI), especially soluble IL-2 receptor (sIL-2R) and IL-8. We aim to evaluate, in MI …

Sodium-glucose cotransporter 2 inhibitors, inflammation, and heart failure: a two-sample Mendelian randomization study

W Guo, L Zhao, W Huang, J Chen, T Zhong… - Cardiovascular …, 2024 - Springer
Background Sodium-glucose cotransporter 2 (SGLT-2) inhibitors are increasingly
recognized for their role in reducing the risk and improving the prognosis of heart failure …

Novel biomarkers of inflammation in heart failure with preserved ejection fraction: analysis from a large prospective cohort study

NW Carris, R Mhaskar, E Coughlin, E Bracey… - BMC Cardiovascular …, 2022 - Springer
Background Heart failure with preserved ejection fraction (HFpEF) is a syndrome with a
heterogeneous cluster of causes, including non-resolving inflammation, endothelial …

IL‐2Rα is a potential biomarker for heart failure diagnosis of patients with end‐stage renal disease and haemodialysis

B Lv, Z Wang, Y Suo, S Shao, M Yuan… - ESC Heart …, 2024 - Wiley Online Library
Aims Heart failure (HF) is a leading cause of mortality in patients with end‐stage renal
disease (ESRD) undergoing haemodialysis. Identifying novel predictors of HF is essential …

Construction of an immune-related signature for predicting the ischemic events in patients undergoing carotid endarterectomy

S Li, Q Zhang, L Weng, J Li - Frontiers in Genetics, 2022 - frontiersin.org
Background: Inflammatory responses have drawn more attention to atherosclerosis;
however, the immune-related genes (IRGs) as a prognostic factor in atherosclerotic plaque …