Proanthocyanidins against oxidative stress: from molecular mechanisms to clinical applications

L Yang, D Xian, X Xiong, R Lai, J Song… - BioMed research …, 2018 - Wiley Online Library
Proanthocyanidins (PCs) are naturally occurring polyphenolic compounds abundant in
many vegetables, plant skins (rind/bark), seeds, flowers, fruits, and nuts. Numerous in vitro …

The value of universally available raw NMR data for transparency, reproducibility, and integrity in natural product research

JB McAlpine, SN Chen, A Kutateladze… - Natural product …, 2019 - pubs.rsc.org
Covering: up to 2018 With contributions from the global natural product (NP) research
community, and continuing the Raw Data Initiative, this review collects a comprehensive …

Polyphenols in dental applications

N Kharouf, Y Haikel, V Ball - Bioengineering, 2020 - mdpi.com
(1) Background: polyphenols are a broad class of molecules extracted from plants and have
a large repertoire of biological activities. Biomimetic inspiration from the effects of tea or red …

Unveiling structure–activity relationships of proanthocyanidins with dentin collagen

M Reis, B Zhou, Y Alania, AA Leme-Kraus, S Jing… - Dental Materials, 2021 - Elsevier
Objective To elucidate the structure–activity relationships (SARs) of proanthocyanidins
(PACs) with type I collagen using sixteen chemically defined PACs with degree of …

Evidence to the role of interflavan linkages and galloylation of proanthocyanidins at sustaining long-term dentin biomodification

B Aydin, AA Leme-Kraus, CMP Vidal, TR Aguiar… - Dental Materials, 2019 - Elsevier
Objectives The interactivity of proanthocyanidins (PACs) with collagen modulates dentin
matrix biomechanics and biostability. Herein, PAC extracts selected based on structural …

Efficacy of new natural biomodification agents from Anacardiaceae extracts on dentin collagen cross-linking

MA Moreira, NO Souza, RS Sousa, DQ Freitas… - Dental materials, 2017 - Elsevier
Objectives Several polyphenols from renewable sources were surveyed for dentin
biomodification. However, phenols from cashew nut shell liquid (CNSL, Anacardium …

Quantum mechanical NMR full spin analysis in pharmaceutical identity testing and quality control

PS Achanta, BU Jaki, JB McAlpine, JB Friesen… - … of pharmaceutical and …, 2021 - Elsevier
Issues related to pharmaceutical quality are arising at an alarming rate. Pharmaceutical
quality concerns both the Active Pharmaceutical Ingredients (APIs) and the Finished Drug …

Structure elucidation of small organic molecules by contemporary computational chemistry methods

CS Kim, J Oh, TH Lee - Archives of Pharmacal Research, 2020 - Springer
Small molecules derived from natural sources such as plants, fungi, bacteria, or synthetic
materials have served as promising drug candidates for a long time. Unambiguous …

Cross-linked dry bonding: A new etch-and-rinse technique

J Zhou, A Chiba, DLS Scheffel, J Hebling, K Agee… - Dental Materials, 2016 - Elsevier
Objective To determine if acid-etched, cross-linked dentin can be dehydrated without
lowering bond strength below that of cross-linked wet-bonded dentin in vitro. Methods Using …

Evolution of Quantitative Measures in NMR: Quantum Mechanical qHNMR Advances Chemical Standardization of a Red Clover (Trifolium pratense) Extract

RS Phansalkar, C Simmler, J Bisson… - Journal of natural …, 2017 - ACS Publications
Chemical standardization, along with morphological and DNA analysis ensures the
authenticity and advances the integrity evaluation of botanical preparations. Achievement of …