Advanced in vitro models of human skeletal muscle tissue are increasingly needed to model
complex developmental dynamics and disease mechanisms not recapitulated in animal …

Introduction With the advances in skeletal muscle tissue engineering, new platforms have
arisen with important applications in biology studies, disease modeling, and drug testing …

In vitro organoids derived from human pluripotent stem cells (hPSCs) have been developed
as essential tools to study the underlying mechanisms of human development and diseases …

Engineering models of human skeletal muscle tissue provides unique translational
opportunities to investigate and develop therapeutic strategies for acute muscle injuries, and …

Skeletal muscle, which comprises a significant portion of the body, is responsible for vital
functions such as movement, metabolism, and overall health. However, severe injuries often …

Large numbers of Calpain 3 (CAPN3) mutations cause recessive forms of limb‐girdle
muscular dystrophy (LGMD2A/LGMDR1) with selective atrophy of the proximal limb …

Human pluripotent stem cells (PSCs), which have the capacity to self-renew and differentiate
into multiple cell types, offer tremendous therapeutic potential and invaluable flexibility as …

Familial amyotrophic lateral sclerosis (ALS) is a progressive neuromuscular disorder that is
due to mutations in one of several target genes, including SOD1. So far, clinical records …

Cell therapies derived from induced pluripotent stem cells (iPSCs) offer a promising avenue
in the field of regenerative medicine due to iPSCs' expandability, immune compatibility, and …

Satellite cells (SCs) and fibroadipogenic progenitors (FAPs) are progenitor populations
found in muscle that form new myofibers postinjury. Muscle development, regeneration, and …