The gut microbiome as a modulator of healthy ageing

TS Ghosh, F Shanahan, PW O'Toole - … Reviews Gastroenterology & …, 2022 - nature.com
The gut microbiome is a contributory factor in ageing-related health loss and in several non-
communicable diseases in all age groups. Some age-linked and disease-linked …

A systematic review of gut microbiota composition in observational studies of major depressive disorder, bipolar disorder and schizophrenia

AJ McGuinness, JA Davis, SL Dawson… - Molecular …, 2022 - nature.com
The emerging understanding of gut microbiota as 'metabolic machinery'influencing many
aspects of physiology has gained substantial attention in the field of psychiatry. This is …

The gut microbiota in inflammatory bowel disease

P Qiu, T Ishimoto, L Fu, J Zhang, Z Zhang… - Frontiers in cellular and …, 2022 - frontiersin.org
Epidemiological surveys indicate that the incidence of inflammatory bowel disease (IBD) is
increasing rapidly with the continuous growth of the economy. A large number of studies …

Akkermansia muciniphila and Gut Immune System: A Good Friendship That Attenuates Inflammatory Bowel Disease, Obesity, and Diabetes

VF Rodrigues, J Elias-Oliveira, ÍS Pereira… - Frontiers in …, 2022 - frontiersin.org
Akkermansia muciniphila is a Gram-negative anaerobic mucus-layer-degrading bacterium
that colonizes the intestinal mucosa of humans and rodents. Metagenomic data have shown …

Multiomics to elucidate inflammatory bowel disease risk factors and pathways

M Agrawal, KH Allin, F Petralia, JF Colombel… - Nature reviews …, 2022 - nature.com
Inflammatory bowel disease (IBD) is an immune-mediated disease of the intestinal tract, with
complex pathophysiology involving genetic, environmental, microbiome, immunological and …

Akkermansia muciniphila alleviates dextran sulfate sodium (DSS)-induced acute colitis by NLRP3 activation

S Qu, L Fan, Y Qi, C Xu, Y Hu, S Chen, W Liu… - Microbiology …, 2021 - Am Soc Microbiol
Akkermansia muciniphila has been proved to play a crucial role in the progression of colitis,
but its underlying mechanism remains inconclusive. In this study, we aim to investigate the …

Chemically and biologically engineered bacteria‐based delivery systems for emerging diagnosis and advanced therapy

Z Li, Y Wang, J Liu, P Rawding, J Bu… - Advanced …, 2021 - Wiley Online Library
Bacteria are one of the main groups of organisms, which dynamically and closely participate
in human health and disease development. With the integration of chemical biotechnology …

Two-sample Mendelian randomization analysis investigates causal associations between gut microbial genera and inflammatory bowel disease, and specificity …

B Liu, D Ye, H Yang, J Song, X Sun, Y Mao… - Frontiers in …, 2022 - frontiersin.org
Background Intestinal dysbiosis is associated with inflammatory bowel disease (IBD).
Ulcerative colitis (UC) and Crohn's disease (CD), two subtypes of IBD, are characterized by …

Microbiome and metabolome features in inflammatory bowel disease via multi-omics integration analyses across cohorts

L Ning, YL Zhou, H Sun, Y Zhang, C Shen… - Nature …, 2023 - nature.com
The perturbations of the gut microbiota and metabolites are closely associated with the
progression of inflammatory bowel disease (IBD). However, inconsistent findings across …

[HTML][HTML] Gut microbial dysbiosis in the pathogenesis of gastrointestinal dysmotility and metabolic disorders

R Singh, H Zogg, L Wei, A Bartlett… - Journal of …, 2021 - ncbi.nlm.nih.gov
Of all microorganisms in the human body, the largest and most complex population resides
in the gastrointestinal (GI) tract. The gut microbiota continuously adapts to the host …