Major differences between men and women exist in epidemiology, manifestation,
pathophysiology, treatment, and outcome of cardiovascular diseases (CVD), such as …

Doxorubicin (DOX) is an anticancer anthracycline that presents a dose‐dependent and
cumulative cardiotoxicity as one of the most serious side effects. Several hypotheses have …

Nearly one-third of deaths in the United States are caused by cardiovascular disease (CVD)
each year. In the past, CVD was thought to mainly affect men, leading to the exclusion of …

The manifestations of cardiovascular diseases differ between men and women, as do
outcomes after therapeutic interventions. It is important that those involved in drug discovery …

Myocardial ischemia–reperfusion (IR) injury is a major contributor to the morbidity and
mortality associated with coronary artery disease. Muscular exercise is a countermeasure to …

Despite a high prevalence of sudden cardiac death throughout the world, the mechanisms
that lead to ventricular arrhythmias are not fully understood. Over the last 20 years, a …

The use of short-term (1–5 days) treadmill running is becoming increasingly common as a
model to study physiological adaptations following the exercise. Although the beneficial …

After myocardial infarction (MI), the heart undergoes extensive myocardial remodeling
through the accumulation of fibrous tissue in both the infarcted and noninfarcted …

BACKGROUND: A sexual dimorphism in human life expectancy has existed in almost every
country for as long as records have been kept. Although human life expectancy has …

Ischaemic heart disease (IHD) is a complex disorder and a leading cause of death and
morbidity in both men and women. Sex, however, affects several aspects of IHD, including …