[HTML][HTML] Immune responses and immunopathology in acute and chronic viral hepatitis
Hepatitis A virus (HAV), hepatitis B virus (HBV) and hepatitis C virus (HCV) are responsible
for most cases of viral hepatitis. Infection by each type of virus results in a different typical …
for most cases of viral hepatitis. Infection by each type of virus results in a different typical …
The history of hepatitis C virus (HCV): Basic research reveals unique features in phylogeny, evolution and the viral life cycle with new perspectives for epidemic control
J Bukh - Journal of hepatology, 2016 - Elsevier
The discovery of hepatitis C virus (HCV) in 1989 permitted basic research to unravel critical
components of a complex life cycle for this important human pathogen. HCV is a highly …
components of a complex life cycle for this important human pathogen. HCV is a highly …
Optical technologies for the detection of viruses like COVID-19: Progress and prospects
The outbreak of life-threatening pandemic like COVID-19 necessitated the development of
novel, rapid and cost-effective techniques that facilitate detection of viruses like SARS-CoV …
novel, rapid and cost-effective techniques that facilitate detection of viruses like SARS-CoV …
[HTML][HTML] Innate and adaptive immune responses in HCV infections
MH Heim, R Thimme - Journal of hepatology, 2014 - Elsevier
Hepatitis C virus has been identified a quarter of a decade ago as a leading cause of
chronic viral hepatitis that can lead to cirrhosis and hepatocellular carcinoma. Only a …
chronic viral hepatitis that can lead to cirrhosis and hepatocellular carcinoma. Only a …
[HTML][HTML] Virology and cell biology of the hepatitis C virus life cycle–An update
J Dubuisson, FL Cosset - Journal of hepatology, 2014 - Elsevier
Hepatitis C virus (HCV) is an important human pathogen that causes hepatitis, liver cirrhosis
and hepatocellular carcinoma. It imposes a serious problem to public health in the world as …
and hepatocellular carcinoma. It imposes a serious problem to public health in the world as …
Type I interferons in viral control and immune regulation
JR Teijaro - Current opinion in virology, 2016 - Elsevier
Highlights•IFN-I signaling has recently been shown to contribute to viral immune
pathologies.•Elevated IFN-I signatures are found in persistent virus infections in multiple …
pathologies.•Elevated IFN-I signatures are found in persistent virus infections in multiple …
The RSPO–LGR4/5–ZNRF3/RNF43 module controls liver zonation and size
L Planas-Paz, V Orsini, L Boulter, D Calabrese… - Nature cell …, 2016 - nature.com
LGR4/5 receptors and their cognate RSPO ligands potentiate Wnt/β-catenin signalling and
promote proliferation and tissue homeostasis in epithelial stem cell compartments. In the …
promote proliferation and tissue homeostasis in epithelial stem cell compartments. In the …
[HTML][HTML] Immunomodulatory role of interferons in viral and bacterial infections
P Mertowska, K Smolak, S Mertowski… - International journal of …, 2023 - mdpi.com
Interferons are a group of immunomodulatory substances produced by the human immune
system in response to the presence of pathogens, especially during viral and bacterial …
system in response to the presence of pathogens, especially during viral and bacterial …
[HTML][HTML] Endogenous intrahepatic IFNs and association with IFN-free HCV treatment outcome
EG Meissner, D Wu, A Osinusi, D Bon… - The Journal of …, 2014 - Am Soc Clin Investig
BACKGROUND. Hepatitis C virus (HCV) infects approximately 170 million people worldwide
and may lead to cirrhosis and hepatocellular carcinoma in chronically infected individuals …
and may lead to cirrhosis and hepatocellular carcinoma in chronically infected individuals …
Immunological analysis during interferon-free therapy for chronic hepatitis C virus infection reveals modulation of the natural killer cell compartment
M Spaan, G van Oord, K Kreefft, J Hou… - The Journal of …, 2016 - academic.oup.com
Background. Chronic hepatitis C virus (HCV) infection is a global health problem, resulting
in liver failure, hepatocellular carcinoma, and liver-related death. Natural killer (NK) cells are …
in liver failure, hepatocellular carcinoma, and liver-related death. Natural killer (NK) cells are …