The biological meaning of radiomic features
MR Tomaszewski, RJ Gillies - Radiology, 2021 - pubs.rsna.org
Radiomic analysis offers a powerful tool for the extraction of clinically relevant information
from radiologic imaging. Radiomics can be used to predict patient outcome through …
from radiologic imaging. Radiomics can be used to predict patient outcome through …
Fibrosis and cancer: A strained relationship
Tumors are characterized by extracellular matrix (ECM) deposition, remodeling, and cross-
linking that drive fibrosis to stiffen the stroma and promote malignancy. The stiffened stroma …
linking that drive fibrosis to stiffen the stroma and promote malignancy. The stiffened stroma …
Early detection of pancreatic cancer
Pancreatic ductal adenocarcinoma is most frequently detected at an advanced stage. Such
late detection restricts treatment options and contributes to a dismal 5-year survival rate of 3 …
late detection restricts treatment options and contributes to a dismal 5-year survival rate of 3 …
[HTML][HTML] Early detection of pancreatic cancer: opportunities and challenges
Most patients with pancreatic ductal adenocarcinoma (PDAC) present with symptomatic,
surgically unresectable disease. Although the goal of early detection of PDAC is laudable …
surgically unresectable disease. Although the goal of early detection of PDAC is laudable …
[HTML][HTML] Artificial intelligence and early detection of pancreatic cancer: 2020 summative review
Despite considerable research efforts, pancreatic cancer is associated with a dire prognosis
and a 5-year survival rate of only 10%. Early symptoms of the disease are mostly …
and a 5-year survival rate of only 10%. Early symptoms of the disease are mostly …
[HTML][HTML] The PDAC extracellular matrix: a review of the ECM protein composition, tumor cell interaction, and therapeutic strategies
Pancreatic ductal adenocarcinoma (PDAC) is notorious for a dense fibrotic stroma that is
interlaced with a collagen-based extracellular matrix (ECM) that plays an important role in …
interlaced with a collagen-based extracellular matrix (ECM) that plays an important role in …
[HTML][HTML] Mitochondrial fusion exploits a therapeutic vulnerability of pancreatic cancer
Pancreatic ductal adenocarcinoma (PDAC) requires mitochondrial oxidative
phosphorylation (OXPHOS) to fuel its growth; however, broadly inhibiting this pathway might …
phosphorylation (OXPHOS) to fuel its growth; however, broadly inhibiting this pathway might …
Radiomics improves cancer screening and early detection
RJ Gillies, MB Schabath - Cancer Epidemiology, Biomarkers & Prevention, 2020 - AACR
Imaging is a key technology in the early detection of cancers, including X-ray
mammography, low-dose CT for lung cancer, or optical imaging for skin, esophageal, or …
mammography, low-dose CT for lung cancer, or optical imaging for skin, esophageal, or …
CT radiomic features of superior mesenteric artery involvement in pancreatic ductal adenocarcinoma: a pilot study
Background Current imaging methods for prediction of complete margin resection (R0) in
patients with pancreatic ductal adenocarcinoma (PDAC) are not reliable. Purpose To …
patients with pancreatic ductal adenocarcinoma (PDAC) are not reliable. Purpose To …
Radiomics signature of brain metastasis: prediction of EGFR mutation status
Objectives To predict epidermal growth factor receptor (EGFR) mutation status in lung
adenocarcinoma using MR-based radiomics signature of brain metastasis and explore the …
adenocarcinoma using MR-based radiomics signature of brain metastasis and explore the …