Reassessing Human Adipose Tissue Adipose tissue can more than double in mass and
then return to baseline. This review discusses the functional roles of human white and brown …

The prevalence of obesity has reached pandemic proportions, and now approximately 25%
of adults in Westernized countries have obesity. Recognized as a major health concern …

White fat stores excess energy, whereas brown and beige fat are thermogenic and dissipate
energy as heat. Thermogenic adipose tissues markedly improve glucose and lipid …

Brown and beige adipocytes are mitochondria-enriched cells capable of dissipating energy
in the form of heat. These thermogenic fat cells were originally considered to function solely …

Adipose tissue plays essential roles in maintaining lipid and glucose homeostasis. To date
several types of adipose tissue have been identified, namely white, brown, and beige, that …

Glucose uptake is essential for cancer glycolysis and is involved in non-shivering
thermogenesis of adipose tissues,,,,–. Most cancers use glycolysis to harness energy for …

Gender and biological sex impact the pathogenesis of numerous diseases, including
metabolic disorders such as diabetes. In most parts of the world, diabetes is more prevalent …

Mammalian adipose tissue can be divided into two major types, namely, white adipose
tissue (WAT) and brown adipose tissue (BAT). According to classical view, the main function …

The proliferator-activated receptor γ (PPARγ), a member of the nuclear receptor superfamily,
is one of the most extensively studied ligand-inducible transcription factors. Since its …

Investigations into the mixed muscle–secretory phenotype of cardiomyocytes from the atrial
appendages of the heart led to the discovery that these cells produce, in a regulated …