Modeling inflammation in zebrafish for the development of anti-inflammatory drugs

Y Xie, AH Meijer, MJM Schaaf - Frontiers in cell and developmental …, 2021 - frontiersin.org
Dysregulation of the inflammatory response in humans can lead to various inflammatory
diseases, like asthma and rheumatoid arthritis. The innate branch of the immune system …

Commensal microbiota regulate vertebrate innate immunity-insights from the zebrafish

CC Murdoch, JF Rawls - Frontiers in immunology, 2019 - frontiersin.org
Microbial communities populate the mucosal surfaces of all animals. Metazoans have co-
evolved with these microorganisms, forming symbioses that affect the molecular and cellular …

Enteroendocrine cells sense bacterial tryptophan catabolites to activate enteric and vagal neuronal pathways

L Ye, M Bae, CD Cassilly, SV Jabba, DW Thorpe… - Cell host & …, 2021 - cell.com
The intestinal epithelium senses nutritional and microbial stimuli using epithelial sensory
enteroendocrine cells (EEC). EECs communicate nutritional information to the nervous …

High fat diet induces microbiota-dependent silencing of enteroendocrine cells

L Ye, O Mueller, J Bagwell, M Bagnat, RA Liddle… - Elife, 2019 - elifesciences.org
Enteroendocrine cells (EECs) are specialized sensory cells in the intestinal epithelium that
sense and transduce nutrient information. Consumption of dietary fat contributes to …

Feed restriction modulates growth, gut morphology and gene expression in zebrafish

K Purushothaman, JKH Tan, D Lau, JM Saju… - International Journal of …, 2021 - mdpi.com
A reduction in daily caloric or nutrient intake has been observed to promote health benefits
in mammals and other vertebrates. Feed Restriction (FR), whereby the overall food intake of …

Deficiency in the cell-adhesion molecule dscaml1 impairs hypothalamic CRH neuron development and perturbs normal neuroendocrine stress axis function

M Ma, AA Brunal, KC Clark, C Studtmann… - Frontiers in Cell and …, 2023 - frontiersin.org
The corticotropin-releasing hormone (CRH)-expressing neurons in the hypothalamus are
critical regulators of the neuroendocrine stress response pathway, known as the …

[PDF][PDF] Manxiu Ma1, Alyssa A. Brunal1, 2, Kareem C. Clark1, Carleigh Studtmann1, 2, Katelyn Stebbins1, 2, 3

S Higashijima, YA Pan - 2023 - vtechworks.lib.vt.edu
The hypothalamic corticotropin-releasing hormone (CRH)-expressing neurons are the
central regulators of the neuroendocrine stress response pathway, known as the …

A Review Of Inflammatory Bowel Disease Study On Zebra Fish And Its Herbal Cure

S Lavanya, K Gowri, V Chitra - NVEO-NATURAL VOLATILES & …, 2021 - nveo.org
Abstract (IBD) Inflammatory bowel disease refers to a group of illnesses characterised by
Prolonged inflammation of the gastrointestinal tract. IBD comprised of two kinds:(UC) …

Compositions and methods for modulating trp channel activity

J Rawls, YE Lihua, R Liddle, SE Jordt… - US Patent App. 17 …, 2023 - Google Patents
US20230149355A1 - Compositions and methods for modulating trp channel activity - Google
Patents US20230149355A1 - Compositions and methods for modulating trp channel activity …

[PDF][PDF] Enteroendocrine cells sense bacterial tryptophan catabolites to activate enteric and vagal neuronal pathways

JD Thompson, CR Lickwar, KD Poss, SE Jordt… - scholar.archive.org
The intestinal epithelium senses nutritional and microbial stimuli using epithelial sensory
enteroendocrine cells (EECs). EECs can communicate nutritional information to the nervous …