Ovarian cancer immunotherapy and personalized medicine

S Morand, M Devanaboyina, H Staats… - International Journal of …, 2021 - mdpi.com
Ovarian cancer response to immunotherapy is limited; however, the evaluation of
sensitive/resistant target treatment subpopulations based on stratification by tumor …

Epidemiology of triple-negative breast cancer: a review

FM Howard, OI Olopade - The Cancer Journal, 2021 - journals.lww.com
Triple-negative breast cancer accounted for 12% of breast cancers diagnosed in the United
States from 2012 to 2016, with a 5-year survival 8% to 16% lower than hormone receptor …

Event-free survival with pembrolizumab in early triple-negative breast cancer

P Schmid, J Cortes, R Dent, L Pusztai… - … England Journal of …, 2022 - Mass Medical Soc
Background The addition of pembrolizumab to neoadjuvant chemotherapy led to a
significantly higher percentage of patients with early triple-negative breast cancer having a …

[HTML][HTML] Clinical significance and biology of circulating tumor DNA in high-risk early-stage HER2-negative breast cancer receiving neoadjuvant chemotherapy

MJM Magbanua, LB Swigart, Z Ahmed, RW Sayaman… - Cancer cell, 2023 - cell.com
Circulating tumor DNA (ctDNA) analysis may improve early-stage breast cancer treatment
via non-invasive tumor burden assessment. To investigate subtype-specific differences in …

Overcoming the blood–brain barrier for the therapy of malignant brain tumor: current status and prospects of drug delivery approaches

K Mitusova, OO Peltek, TE Karpov… - Journal of …, 2022 - Springer
Besides the broad development of nanotechnological approaches for cancer diagnosis and
therapy, currently, there is no significant progress in the treatment of different types of brain …

The obesity-breast cancer link: a multidisciplinary perspective

EN Devericks, MS Carson, LE McCullough… - Cancer and Metastasis …, 2022 - Springer
Obesity, exceptionally prevalent in the USA, promotes the incidence and progression of
numerous cancer types including breast cancer. Complex, interacting metabolic and …

Annual report to the nation on the status of cancer, featuring cancer in men and women age 20–49 years

EM Ward, RL Sherman, SJ Henley… - JNCI: Journal of the …, 2019 - academic.oup.com
Abstract Background The American Cancer Society, Centers for Disease Control and
Prevention, National Cancer Institute, and North American Association of Central Cancer …

Emerging targeted therapies for HER2-positive breast cancer

MF Mercogliano, S Bruni, FL Mauro, R Schillaci - Cancers, 2023 - mdpi.com
Simple Summary HER2-positive breast cancer (BC), which accounts for~ 20% of BC, is one
of the more aggressive and has the worst overall survival rate among them. These patients …

Breast cancer statistics, 2019

CE DeSantis, J Ma, MM Gaudet… - CA: a cancer journal …, 2019 - Wiley Online Library
This article is the American Cancer Society's biennial update on female breast cancer
statistics in the United States, including data on incidence, mortality, survival, and screening …

The tale of TILs in breast cancer: a report from the international immuno-oncology biomarker working group

K El Bairi, HR Haynes, E Blackley, S Fineberg… - NPJ breast …, 2021 - nature.com
The advent of immune-checkpoint inhibitors (ICI) in modern oncology has significantly
improved survival in several cancer settings. A subgroup of women with breast cancer (BC) …