Multifunctional hybrid nanoparticles in diagnosis and therapy of breast cancer

N Rajana, A Mounika, PS Chary, V Bhavana… - Journal of Controlled …, 2022 - Elsevier
Breast cancer is the most prevalent non-cutaneous malignancy in women, with greater than
a million new cases every year. In the last decennium, numerous diagnostic and treatment …

A review of the structure, preparation, and application of NLCs, PNPs, and PLNs

Q Li, T Cai, Y Huang, X Xia, SPC Cole, Y Cai - Nanomaterials, 2017 - mdpi.com
Nanostructured lipid carriers (NLCs) are modified solid lipid nanoparticles (SLNs) that retain
the characteristics of the SLN, improve drug stability and loading capacity, and prevent drug …

[HTML][HTML] Lipid polymer hybrid nanocarriers: Insights into synthesis aspects, characterization, release mechanisms, surface functionalization and potential implications

S Shah, P Famta, RS Raghuvanshi, SB Singh… - Colloid and Interface …, 2022 - Elsevier
Lipid polymer hybrid nanoparticles (LPHN) are novel systems which are potentially
emerging in the era of nano-medicine. They are core-shell nanostructures which comprise of …

Development and optimization of methotrexate-loaded lipid-polymer hybrid nanoparticles for controlled drug delivery applications

N Tahir, A Madni, V Balasubramanian… - International journal of …, 2017 - Elsevier
Lipid-polymer hybrid nanoparticles (LPHNPs) are emerging platforms for drug delivery
applications. In the present study, methotrexate loaded LPHNPs consisted of PLGA and …

Quality by Design (QbD)-enabled development of aceclofenac loaded-nano structured lipid carriers (NLCs): An improved dermatokinetic profile for inflammatory …

NK Garg, G Sharma, B Singh, P Nirbhavane… - International Journal of …, 2017 - Elsevier
Present study was designed to prepare and characterize aceclofenac loaded
nanostructured lipid carriers (NLCs) employing Quality by Design (QbD)-oriented approach …

Lipid poly (ɛ-caprolactone) hybrid nanoparticles of 5-fluorouracil for sustained release and enhanced anticancer efficacy

S Khan, MN Aamir, A Madni, N Jan, A Khan, A Jabar… - Life Sciences, 2021 - Elsevier
Aims The present study aimed to develop and characterize poly (ɛ-caprolactone)(PCL)
based lipid polymer hybrid nanoparticles for sustained delivery and in-vitro anti-cancer …

Multifunctional folate receptor-targeting and pH-responsive nanocarriers loaded with methotrexate for treatment of rheumatoid arthritis

J Zhao, M Zhao, C Yu, X Zhang, J Liu… - International journal …, 2017 - Taylor & Francis
Rheumatoid arthritis (RA) is an autoimmune disease characterized by progressive cartilage
and bone destruction. Activated macrophages that overexpress folic acid (FA) receptors play …

Methotrexate and beta-carotene loaded-lipid polymer hybrid nanoparticles: A preclinical study for breast cancer

A Jain, G Sharma, V Kushwah, NK Garg… - …, 2017 - Taylor & Francis
Aim: This work was intended to investigate the targeting potential of fructose-tethered lipid-
polymeric hybrid nanoparticles (F-BC-MTX-LPHNPs) co-loaded with beta carotene (BC) and …

Nanoparticulate drugs and vaccines: breakthroughs and bottlenecks of repurposing in breast cancer

P Kumbhar, K Kole, V Khadake, P Marale… - Journal of Controlled …, 2022 - Elsevier
Breast cancer (BC) is a highly diagnosed and topmost cause of death in females worldwide.
Drug repurposing (DR) has shown great potential against BC by overcoming major …

Nanostructured lipid carrier mediates effective delivery of methotrexate to induce apoptosis of rheumatoid arthritis via NF-κB and FOXO1

NK Garg, RK Tyagi, B Singh, G Sharma… - International journal of …, 2016 - Elsevier
Present study was designed to develop novel nano-structured lipid carriers (NLCs)
formulated by lipid mixture and chemical permeation enhancer-based hydrogel for an …