Staphylococcus aureus strains causing human pathologies produce several toxins,
including a pore-forming protein family formed by the single-component α-hemolysin and …

Urease, a nickel-dependent metalloenzyme, is synthesized by plants, some bacteria, and
fungi. It catalyzes the hydrolysis of urea into ammonia and carbon dioxide. Although the …

As data accumulates, the newer antimicrobial agents active against community-acquired
MRSA continue to demonstrate their value. Despite the appeal and abundant publications …

The staphylococcal α‐hemolysin (αHL) and leukocidin (Luk) polypeptides are members of a
family of related β‐barrel pore‐forming toxins. Upon binding to susceptible cells, αHL forms …

Methicillin-resistant Staphylococcus aureus (MRSA) has emerged as an important cause of
skin and soft-tissue infections (SSTI). The understanding of the molecular epidemiology and …

Staphylococcal γ-hemolysins are bicomponent toxins forming a protein family with
leucocidins and α-toxin. Two active toxins (AB and CB) can be formed combining one of the …

The natural target of Staphylococcus aureus bicomponent γ-hemolysins are leucocyte cell
membranes. Because a proteinaceous receptor has not been found yet, we checked for the …

Résumé La bactérie Staphylococcus aureus est responsable de nombreux types
d'infections chez l'homme et compte parmi les agents pathogènes les plus souvent isolés …

Staphylococcal leucotoxins, leucocidins, and γ‐hemolysins are bicomponent β‐barrel pore‐
forming toxins (β‐PFTs). Their production is associated with several clinical diseases. They …

The range of leucocytes susceptible to the leucotoxin LukM/F′, a two-component pore-
forming toxin of Staphylococcus aureus causing mastitis in ruminants, had not been defined …