Escherichia coli sequence type 131 (ST131) and Klebsiella pneumoniae ST258 emerged in
the 2000s as important human pathogens, have spread extensively throughout the world …

Abstract The Working Party makes more than 100 tabulated recommendations in
antimicrobial prescribing for the treatment of infections caused by multidrug-resistant (MDR) …

CTX-M β-lactamases are considered a paradigm in the evolution of a resistance
mechanism. Incorporation of different chromosomal bla CTX-M related genes from different …

Background: Since the initial appearance in the 1980s, Enterobacteriaceae producing
extended-spectrum β-lactamase (ESBL) have increased in prevalence and emerged as a …

Multilocus sequence typing reveals that many bacterial species have a clonal structure and
that some clones are widespread. This underlying phylogeny was not revealed by pulsed …

Pathogenic Escherichia coli strains cause a wide variety of intestinal and extraintestinal
infections. The widespread geographical clonal dissemination of intestinal pathogenic E …

Extended-spectrum β-lactamases (ESBLs) are a rapidly evolving group of β-lactamases
which share the ability to hydrolyze third-generation cephalosporins and aztreonam yet are …

The medical community relies on clinical expertise and published guidelines to assist
physicians with choices in empirical therapy for system-based infectious syndromes, such as …

The treatment of bacterial infections is increasingly complicated by the ability of bacteria to
develop resistance to antimicrobial agents. Antimicrobial agents are often categorized …

Escherichia coli sequence type 131 (ST131) is a worldwide pandemic clone, causing
predominantly community-onset antimicrobial-resistant infection. Its pandemic spread was …