[HTML][HTML] Harnessing the immune system: an effective way to manage diffuse large B-cell lymphoma

N Visweshwar, JF Rico, R Killeen… - Journal of …, 2023 - ncbi.nlm.nih.gov
Diffuse large B-cell lymphoma (DLBCL) is a heterogenous hematological disorder with
malignant potential controlled by immunological characteristics of the tumor …

The diverse landscape of dermatologic toxicities of non‐immune checkpoint inhibitor monoclonal antibody‐based cancer therapy

RNH Seervai, SK Friske, EY Chu… - Journal of cutaneous …, 2023 - Wiley Online Library
Background Since their first approval 25 years ago, monoclonal antibodies (mAbs) have
become important targeted cancer therapeutics. However, dermatologic toxicities associated …

Time‐dependent clearance can confound exposure–response analysis of therapeutic antibodies: A comprehensive review of the current literature

JR Proctor, H Wong - Clinical and Translational Science, 2024 - Wiley Online Library
Exposure–response (ER) analysis is used to optimize dose and dose regimens during
clinical development. Characterization of relationships between drug exposure and efficacy …

Loncastuximab tesirine: Risk for dose variance

PE Kintzel - American Journal of Health-System Pharmacy, 2024 - academic.oup.com
Loncastuximab tesirine is a CD19-directed antibody-drug complex with an alkylating moiety
indicated for third-line treatment of adults with relapsed or refractory large B cell lymphoma …

Lonkastuksimabi-tesiriini diffuusin suurisoluisen B-solulymfooman ja korkean maligniteettiasteen B-solulymfooman hoidossa

J Kotajärvi, M Lamminsalo, A Rahkonen - 2023 - julkari.fi
Tämän arvioinnin kohteena on lonkastuksimabi-tesiriini, joka on tarkoitettu monoterapiana
uusiutuneen tai hoitoon reagoimattoman suurisoluisen B-solulymfooman tai korkean …

Safety of loncastuximab tesirine‐lpyl in diffuse large B‐cell lymphoma with severe hepatic dysfunction

GT Baek, IJ Huang, AK Gopal - Cancer, 2023 - Wiley Online Library
Diffuse large B‐cell lymphoma (DLBCL) is an aggressive subtype of non‐Hodgkin
lymphoma with a high rate of disease relapse despite the achievement of clinical responses …

Variable or variate? A conundrum in pharmacometrics exposure–response models

AM Grisic, K Venkatakrishnan, J French… - CPT …, 2023 - Wiley Online Library
Key elements of scientific writing—consistency and clarity—can be compromised in case of
inaccurate use of methodological terms, especially in complex and multidisciplinary …