Being one of the main proteins in the human body and many animal species, albumin plays
a decisive role in the transport of various ions—electrically neutral and charged molecules …

Obesity is increasingly prevalent and is associated with substantial cardiovascular risk.
Adipose tissue distribution and morphology play a key role in determining the degree of …

The innate immune system includes several classes of pattern recognition receptors (PRRs),
including membrane-bound Toll-like receptors (TLRs) and nucleotide-binding …

Metabolic syndrome and major depression are two of the most common and debilitating
disorders worldwide, occurring with significant rates of comorbidity. Recent studies have …

Damage-associated molecular patterns (DAMPs) are endogenous danger molecules
produced in cellular damage or stress, and they can activate the innate immune system …

Despite all the advances of modern medicine, atherosclerosis continues to be one of the
most important medical and social problems. Atherosclerosis is the cause of several …

Environmental and socioeconomic changes over the past thirty years have contributed to a
dramatic rise in the worldwide prevalence of obesity. Heart disease is amongst the most …

Endothelial cells (ECs) maintain the health of blood vessels and prevent the development of
cardiovascular disease (CVD). Free saturated fatty acids (FAs) induce EC damage and …

Palmitic acid is the predominant dietary saturated fatty acid (SFA) in the US diet. Plasma
palmitic acid is derived from dietary fat and also endogenously from de novo lipogenesis …

The hypothalamus is a critical brain region for the regulation of energy homeostasis. Over
the years, studies on energy metabolism primarily focused on the neuronal component of …