Polyproline-II helix in proteins: structure and function
AA Adzhubei, MJE Sternberg, AA Makarov - Journal of molecular biology, 2013 - Elsevier
The poly-l-proline type II (PPII) helix in recent years has emerged clearly as a structural class
not only of fibrillar proteins (in collagen, PPII is a dominant conformation) but also of the …
not only of fibrillar proteins (in collagen, PPII is a dominant conformation) but also of the …
Feedback regulation of EGFR signalling: decision making by early and delayed loops
R Avraham, Y Yarden - Nature reviews Molecular cell biology, 2011 - nature.com
Human-made information relay systems invariably incorporate central regulatory
components, which are mirrored in biological systems by dense feedback and feedforward …
components, which are mirrored in biological systems by dense feedback and feedforward …
High-resolution global peptide-protein docking using fragments-based PIPER-FlexPepDock
Peptide-protein interactions contribute a significant fraction of the protein-protein
interactome. Accurate modeling of these interactions is challenging due to the vast …
interactome. Accurate modeling of these interactions is challenging due to the vast …
[PDF][PDF] The SH3 domain--a family of versatile peptide-and protein-recognition module
Introduction 3. Conventional and atypical sequence motifs 3.1. Canonical peptide motifs
recognized by the SH3 domains 3.2. Atypical SH3-binding motifs 3.3. The RxxK motif 4 …
recognized by the SH3 domains 3.2. Atypical SH3-binding motifs 3.3. The RxxK motif 4 …
Expanding functions of GIT Arf GTPase-activating proteins, PIX Rho guanine nucleotide exchange factors and GIT–PIX complexes
W Zhou, X Li, RT Premont - Journal of Cell Science, 2016 - journals.biologists.com
The GIT proteins, GIT1 and GIT2, are GTPase-activating proteins (inactivators) for the ADP-
ribosylation factor (Arf) small GTP-binding proteins, and function to limit the activity of Arf …
ribosylation factor (Arf) small GTP-binding proteins, and function to limit the activity of Arf …
Structural basis for recognition of arginine methylated Piwi proteins by the extended Tudor domain
Arginine methylation modulates diverse cellular processes and represents a molecular
signature of germ-line-specific Piwi family proteins. A subset of Tudor domains recognize …
signature of germ-line-specific Piwi family proteins. A subset of Tudor domains recognize …
Cool-1 functions as an essential regulatory node for EGFreceptor-and Src-mediated cell growth
Q Feng, D Baird, X Peng, J Wang, T Ly, JL Guan… - Nature cell …, 2006 - nature.com
Abstract Cool-1 (cloned-out of library 1) has a key role in regulating epidermal growth factor
receptor (EGFR) degradation. Here, we show that Cool-1 performs this function by …
receptor (EGFR) degradation. Here, we show that Cool-1 performs this function by …
Dysregulation of Rho GTPases in the αPix/Arhgef6 mouse model of X-linked intellectual disability is paralleled by impaired structural and synaptic plasticity and …
GJA Ramakers, D Wolfer, G Rosenberger… - Human molecular …, 2012 - academic.oup.com
Mutations in the ARHGEF6 gene, encoding the guanine nucleotide exchange factor
αPIX/Cool-2 for the Rho GTPases Rac1 and Cdc42, cause X-linked intellectual disability (ID) …
αPIX/Cool-2 for the Rho GTPases Rac1 and Cdc42, cause X-linked intellectual disability (ID) …
Molecular mechanisms of ubiquitin-dependent membrane traffic
JH Hurley, H Stenmark - Annual review of biophysics, 2011 - annualreviews.org
Over the past 14 years, ubiquitination has emerged as a centrally important mechanism
governing the subcellular trafficking of proteins. Ubiquitination, interaction with sorting …
governing the subcellular trafficking of proteins. Ubiquitination, interaction with sorting …
E3 ubiquitin ligase Cbl-b in innate and adaptive immunity
Casitas B-lineage lymphoma proto-oncogene-b (Cbl-b), a RING finger E3 ubiquitin-protein
ligase, has been demonstrated to play a crucial role in establishing the threshold for T-cell …
ligase, has been demonstrated to play a crucial role in establishing the threshold for T-cell …