Collective cell migration has a key role during morphogenesis and during wound healing
and tissue renewal in the adult, and it is involved in cancer spreading. In addition to …

The purpose of this review is to provide an overview of redox mechanisms, sources and
antioxidants that control signaling events in ECs. In particular, we describe which molecules …

Pathological angiogenesis frequently occurs in tumor tissue, limiting the efficiency of
chemotherapeutic drug delivery and accelerating tumor progression. However, traditional …

The roles of nitric oxide (NO) and endothelial NO synthase (eNOS) in the regulation of
angiogenesis are well documented. However, the involvement of eNOS in the sprouting of …

Impaired diabetic wounds are one of the major pathophysiological complications caused by
persistent microbial infections, prolonged inflammation, and insufficient angiogenic …

Clinical and epidemiological data show that biological sex is one of the major determinants
for the development and progression of cardiovascular disease (CVD). Impaired endothelial …

Diabetic ulcers, gangrene, local infections and other traumatic symptoms of wound healing
are all directly related. Promoting the early healing of diabetic cutaneous ulcers (DCU) and …

The nitric oxide/soluble guanylyl cyclase (NO-sGC) signaling pathway regulates the
cardiovascular, neuronal, and gastrointestinal systems. Impaired sGC signaling can result in …

Background Paracrine signaling from endothelial progenitor cells (EPCs) is beneficial for
angiogenesis and thus promotes tissue regeneration. Microgravity (MG) environment is …

Vascular sprouting is a key process of angiogenesis and mainly related to the formation of
stalk and tip cells. Many studies have found that angiogenesis has a great clinical …