There exists a paucity of structural innovation and limited molecular diversity associated with
molecular frameworks in drug discovery and biomolecular imaging/chemical probe design …

Boron-containing compounds (BCC) have emerged as important pharmacophores. To date,
five BCC drugs (including boronic acids and boroles) have been approved by the FDA for …

The membrane translocation of hydrophilic substances constitutes a challenge for their
application as therapeutic compounds and labelling probes,,–. To remedy this, charged …

In this review, the history of boron's early use in drugs, and the history of the use of boron
functional groups in medicinal chemistry applications are discussed. This includes …

Following up on scattered reports on interactions of conventional chaotropic ions (for
example, I−, SCN−, ClO4−) with macrocyclic host molecules, biomolecules, and …

Boron cluster compounds are inorganic compounds with chemical compositions and
structures vastly different from those of organic compounds, albeit with the ability to form a …

It has been almost 50 years since the term “supramolecular chemistry” was coined to
describe chemistry beyond the molecule. Since its beginning, supramolecular chemistry has …

Resveratrol is a polyphenol belonging to the class stilbenes. The active and stable form of
resveratrol is trans-resveratrol. This polyphenol is bestowed with numerous biological …

After uptake by U87 MG and A375 cancer cells, cobaltabisdicarbollide [COSAN]− distributes
between membrane and nucleus and presents no relevant cytotoxicity against both cell lines …

Metallacarboranes are a class of inorganic boron clusters that have recently been
recognized as biologically active compounds. Herein, we report on the host–guest …