Massive viral outbreaks draw attention to viruses that have not been thoroughly studied or
understood. In recent decades, microfluidic chips, known as “lab-on-a-chip”, appears as a …

The Flavivirus genus is made up of viruses that are either mosquito-borne or tick-borne and
other viruses transmitted by unknown vectors. Flaviviruses present a significant threat to …

Background Metagenomic next-generation sequencing (mNGS) has enabled the rapid,
unbiased detection and identification of microbes without pathogen-specific reagents …

In low-resource settings, resilience to infectious disease outbreaks can be hindered by
limited access to diagnostic tests. Here we report the results of double-blinded studies of the …

Background Japanese encephalitis (JE) is a viral disease predominantly located in South
East Asia and commonly associated with transmission between amplifying hosts, such as …

Diagnosis of arbovirus infection or exposure by antibody testing is becoming increasingly
difficult due to global expansion of arboviruses, which induce antibodies that may (cross-) …

Viral proteases are diverse in structure, oligomeric state, catalytic mechanism, and substrate
specificity. This chapter focuses on proteases from viruses that are relevant to human health …

Dengue virus is an arbovirus belonging to class Flaviviridae Its clinical manifestation ranges
from asymptomatic to extreme conditions (dengue hemorrhagic fever/dengue shock …

Antibody (Ab)-dependent enhancement can exacerbate dengue virus (DENV) infection due
to cross-reactive Abs from an initial DENV infection, facilitating replication of a second …

The rapid spread of viral infections demands early detection strategies to minimize
proliferation of the disease. Here, we demonstrate a plasmonic biosensor to detect Dengue …