Signaling pathways and targeted therapy for myocardial infarction

Q Zhang, L Wang, S Wang, H Cheng, L Xu… - Signal transduction and …, 2022 - nature.com
Although the treatment of myocardial infarction (MI) has improved considerably, it is still a
worldwide disease with high morbidity and high mortality. Whilst there is still a long way to …

Exercise therapy for people with sarcopenic obesity: myokines and adipokines as effective actors

H Alizadeh Pahlavani - Frontiers in endocrinology, 2022 - frontiersin.org
Sarcopenic obesity is defined as a multifactorial disease in aging with decreased body
muscle, decreased muscle strength, decreased independence, increased fat mass, due to …

Exercise training alleviates cardiac fibrosis through increasing fibroblast growth factor 21 and regulating TGF-β1-Smad2/3-MMP2/9 signaling in mice with myocardial …

Y Ma, Y Kuang, W Bo, Q Liang, W Zhu, M Cai… - International Journal of …, 2021 - mdpi.com
Exercise training has been reported to alleviate cardiac fibrosis and ameliorate heart
dysfunction after myocardial infarction (MI), but the molecular mechanism is still not fully …

Post-myocardial infarction fibrosis: Pathophysiology, examination, and intervention

X Yin, X Yin, X Pan, J Zhang, X Fan, J Li… - Frontiers in …, 2023 - frontiersin.org
Cardiac fibrosis plays an indispensable role in cardiac tissue homeostasis and repair after
myocardial infarction (MI). The cardiac fibroblast-to-myofibroblast differentiation and …

Health-related quality of life (HRQoL) in sarcoidosis: diagnosis, management, and health outcomes

LA Saketkoo, AM Russell, K Jensen, J Mandizha… - Diagnostics, 2021 - mdpi.com
Health-related quality of life (HRQoL), though rarely considered as a primary endpoint in
clinical trials, may be the single outcome reflective of patient priorities when living with a …

Antioxidant therapy against TGF‐β/SMAD pathway involved in organ fibrosis

S Ghafouri‐Fard, A Askari, H Shoorei… - Journal of Cellular …, 2024 - Wiley Online Library
Fibrosis refers to excessive build‐up of scar tissue and extracellular matrix components in
different organs. In recent years, it has been revealed that different cytokines and …

Aerobic exercise ameliorates myocardial fibrosis via affecting vitamin D receptor and transforming growth factor-β1 signaling in vitamin D-deficient mice

X Cui, K Wang, J Zhang, ZB Cao - Nutrients, 2023 - mdpi.com
Myocardial fibrosis is a pathological phenomenon associated with cardiovascular disease
(CVD) that plays a crucial role in the development of heart diseases. Vitamin D deficiency …

Exercise as a multi-modal disease-modifying medicine in systemic sclerosis: An introduction by The Global Fellowship on Rehabilitation and Exercise in Systemic …

H Pettersson, H Alexanderson, JL Poole… - Best practice & research …, 2021 - Elsevier
Systemic sclerosis (SSc) is a heterogeneous multisystem autoimmune disease whereby its
main pathological drivers of disability and damage are vascular injury, inflammatory cell …

[HTML][HTML] Inappropriate use of proton pump inhibitors increases cardiovascular events in patients with coronary heart disease

W Hu, Y Luo, X Yang - International Journal of General Medicine, 2022 - ncbi.nlm.nih.gov
Antiplatelet drugs, as the cornerstone of the treatment of coronary heart disease, control the
progression of the disease, but bring a higher risk of gastrointestinal bleeding. Relevant …

Myocardial angiogenesis induced by concurrent vitamin D supplementation and aerobic-resistance training is mediated by inhibiting miRNA-15a, and miRNA-146a …

A Saati-Zarei, A Damirchi, SMTR Tousi… - Pflügers Archiv-European …, 2023 - Springer
This study aimed to investigate the effects of co-treatment of aerobic-resistance training
(ART), vitamin D3 (VD3) on cardiovascular function considering the involvement of …