Hydrophilic interaction liquid chromatography (HILIC)—a powerful separation technique

B Buszewski, S Noga - Analytical and bioanalytical chemistry, 2012 - Springer
Hydrophilic interaction liquid chromatography (HILIC) provides an alternative approach to
effectively separate small polar compounds on polar stationary phases. The purpose of this …

Stationary and mobile phases in hydrophilic interaction chromatography: a review

P Jandera - Analytica chimica acta, 2011 - Elsevier
Hydrophilic interaction chromatography (HILIC) is valuable alternative to reversed-phase
liquid chromatography separations of polar, weakly acidic or basic samples. In principle, this …

Main interactions and influences of the chromatographic parameters in HILIC separations

G Greco, T Letzel - Journal of chromatographic science, 2013 - academic.oup.com
Hydrophilic interaction liquid chromatography (HILIC) is a popular technique for the
separation of polar compounds, which are poorly retained by reversed-phase liquid …

Stationary phases for hydrophilic interaction chromatography, their characterization and implementation into multidimensional chromatography concepts

P Jandera - Journal of separation science, 2008 - Wiley Online Library
Hydrophilic interaction chromatography (HILIC) is becoming increasingly popular for
separation of polar samples on polar columns in aqueous‐organic mobile phases rich in …

Investigations on the chromatographic behaviour of zwitterionic stationary phases used in hydrophilic interaction chromatography

RI Chirita, C West, S Zubrzycki, AL Finaru… - … of Chromatography a, 2011 - Elsevier
Two commercial stationary phases possessing a sulfobetaine zwitterionic bonded ligand
(ZIC-HILIC and Nucleodur HILIC) were compared under hydrophilic interaction …

HILIC methods in pharmaceutical analysis

B Dejaegher, Y Vander Heyden - Journal of separation science, 2010 - Wiley Online Library
In this review, hydrophilic interaction liquid chromatographic (HILIC) applications for
pharmaceutical analysis are discussed. The HILIC technique uses an aqueous/organic …

Study on the retention equation in hydrophilic interaction liquid chromatography

G Jin, Z Guo, F Zhang, X Xue, Y Jin, X Liang - Talanta, 2008 - Elsevier
Hydrophilic interaction liquid chromatography (HILIC) is an effective technique for
separating polar compounds. But its retention equation has not been studied systematically …

Chemometric-assisted method development in hydrophilic interaction liquid chromatography: a review

M Taraji, PR Haddad, RIJ Amos, M Talebi, R Szucs… - Analytica chimica …, 2018 - Elsevier
With an enormous growth in the application of hydrophilic interaction liquid chromatography
(HILIC), there has also been significant progress in HILIC method development. HILIC is a …

Synthesis, chromatographic evaluation and hydrophilic interaction/reversed-phase mixed-mode behavior of a “Click β-cyclodextrin” stationary phase

Z Guo, Y Jin, T Liang, Y Liu, Q Xu, X Liang… - … of Chromatography A, 2009 - Elsevier
A native β-cyclodextrin (β-CD) stationary phase was prepared by covalently bonding β-CD
on silica particles via Huisgen [3+ 2] dipolar cycloaddition between the organic azide and …

Prediction of chromatographic retention time in high-resolution anti-doping screening data using artificial neural networks

TH Miller, A Musenga, DA Cowan… - Analytical chemistry, 2013 - ACS Publications
The computational generation of gradient retention time data for retrospective detection of
suspected sports doping species in postanalysis human urine sample data is presented …