Antidepressant Potential of Quercetin and its Glycoside Derivatives: A Comprehensive Review and Update

S Chen, Y Tang, Y Gao, K Nie, H Wang, H Su… - Frontiers in …, 2022 - frontiersin.org
Depression is a global health problem with growing prevalence rates and serious impacts
on the daily life of patients. However, the side effects of currently used antidepressants …

Long-COVID post-viral chronic fatigue and affective symptoms are associated with oxidative damage, lowered antioxidant defenses and inflammation: a proof of …

HK Al-Hakeim, HT Al-Rubaye, DS Al-Hadrawi… - Molecular …, 2023 - nature.com
The immune-inflammatory response during the acute phase of COVID-19, as assessed
using peak body temperature (PBT) and peripheral oxygen saturation (SpO2), predicts the …

[HTML][HTML] Polyphenols as novel interventions for depression: exploring the efficacy, mechanisms of action, and implications for future research

E Gamage, R Orr, N Travica, MM Lane… - Neuroscience & …, 2023 - Elsevier
Numerous animal and human studies have assessed the relationship between polyphenols
and outcomes related to depression. However, no comprehensive synthesis of the main …

Role of quercetin in depressive-like behaviors: Findings from animal models

S Silvestro, P Bramanti, E Mazzon - Applied Sciences, 2021 - mdpi.com
Depressive-like behavior is a highly prevalent worldwide neuropsychiatric disorder that
owns a complex pathophysiologic mechanism. The available pharmacotherapy is ineffective …

Neuroprotective effects of quercetin in pediatric neurological diseases

L Alvarez-Arellano, M Salazar-García, JC Corona - Molecules, 2020 - mdpi.com
Oxidative stress is a crucial event underlying several pediatric neurological diseases, such
as the central nervous system (CNS) tumors, autism spectrum disorder (ASD) and attention …

The intervention of prebiotics on depression via the Gut–Brain axis

Q He, C Si, Z Sun, Y Chen, X Zhang - Molecules, 2022 - mdpi.com
The imbalance of intestinal microbiota can cause the accumulation of endotoxin in the main
circulation system of the human body, which has a great impact on human health. Increased …

Prolonged maternal separation reduces anxiety state and increases compulsive burying activity in the offspring of BALB/c mice

Q Jarrar, R Ayoub, K Alhussine, KW Goh… - Journal of Personalized …, 2022 - mdpi.com
Background: The elevated plus maze (EPM) and the marble burying (MB) tests are common
behavioral tests used for behavioral phenotyping in mouse models for neurodevelopmental …

[HTML][HTML] Quercetin inhibits chronic stress-mediated progression of triple-negative breast cancer by blocking β2-AR/ERK1/2 pathway

J Zhang, F Teng, T Wu, S Li, K Li - Biomedicine & Pharmacotherapy, 2024 - Elsevier
Chronic stress-mediated sustained release of neurotransmitters, which ultimately leads to
the activation of β 2-adrenergic receptor (β 2-AR) signaling, is one of the most important …

Resveratrol ameliorates physical and psychological stress-induced depressive-like behavior

C Ardianto, AS Budiatin, INB Sumartha… - Journal of basic and …, 2021 - degruyter.com
Objectives Depression is a mental disorder that profoundly affects all aspects of life, but
currently, antidepressants have some problems with their effectiveness and side effects …

Quercetin promotes behavioral recovery and biomolecular changes of melanocortin-4 receptor in mice with ischemic stroke

T Ulya, C Ardianto, P Anggreini, AS Budiatin… - Journal of Basic and …, 2021 - degruyter.com
Objectives Ischemic stroke is known as a common causes of disability, lower psychological
well-being as well as preventable death. The pathogenesis of ischemic stroke process …