This paper briefly reviews the physiological components of the microcirculation, focusing on
its function in homeostasis and its central function in the realization of oxygen transport to …

This article presents a personal viewpoint of the shortcoming of conventional hemodynamic
resuscitation procedures in achieving organ perfusion and tissue oxygenation following …

Purpose Hand-held vital microscopes (HVMs) were introduced to observe sublingual
microcirculatory alterations at the bedside in different shock states in critically ill patients …

Objectives: Sepsis induces microvascular alterations that may play an important role in the
development of organ dysfunction. However, the relationship of these alterations to systemic …

Aggressive fluid resuscitation to achieve a central venous pressure (CVP) greater than 8 mm
Hg has been promoted as the standard of care, in the management of patients with severe …

The primary focus of monitoring anesthetized patients is the assessment of depth of
anesthesia, cardiovascular and pulmonary consequences of the anesthetized state, and …

Background Optimal timing for the start of vasopressors (VP) in septic shock has not been
widely studied since it is assumed that fluids must be administered in advance. We sought to …

Arterial blood pressure is the driving force for organ perfusion. Although hypotension is
common in acute care, there is a lack of accepted criteria for its definition. Most practitioners …

AKI is a common complication of sepsis and is significantly associated with mortality. Sepsis
accounts for more than 50% of the cases of AKI, with a mortality rate of up to 40%. The …

Purpose To discuss the techniques currently available to evaluate the microcirculation in
critically ill patients. In addition, the most clinically relevant microcirculatory alterations will …