Physiological roles of hydrogen sulfide in mammalian cells, tissues, and organs

G Cirino, C Szabo… - Physiological …, 2023 - journals.physiology.org
Over the last two decades, hydrogen sulfide (H2S) has emerged as an endogenous
regulator of a broad range of physiological functions. H2S belongs to the class of molecules …

Chemical Biology of H2S Signaling through Persulfidation

MR Filipovic, J Zivanovic, B Alvarez… - Chemical …, 2018 - ACS Publications
Signaling by H2S is proposed to occur via persulfidation, a posttranslational modification of
cysteine residues (RSH) to persulfides (RSSH). Persulfidation provides a framework for …

Periplasmic biomineralization for semi-artificial photosynthesis

Y Lin, J Shi, W Feng, J Yue, Y Luo, S Chen, B Yang… - Science …, 2023 - science.org
Semiconductor-based biointerfaces are typically established either on the surface of the
plasma membrane or within the cytoplasm. In Gram-negative bacteria, the periplasmic …

A review of hydrogen sulfide synthesis, metabolism, and measurement: is modulation of hydrogen sulfide a novel therapeutic for cancer?

X Cao, L Ding, Z Xie, Y Yang, M Whiteman… - Antioxidants & redox …, 2019 - liebertpub.com
Abstract Significance: Hydrogen sulfide (H2S) has been recognized as the third gaseous
transmitter alongside nitric oxide and carbon monoxide. In the past decade, numerous …

[HTML][HTML] Implications of hydrogen sulfide in colorectal cancer: Mechanistic insights and diagnostic and therapeutic strategies

H Lin, Y Yu, L Zhu, N Lai, L Zhang, Y Guo, X Lin… - Redox Biology, 2023 - Elsevier
Hydrogen sulfide (H 2 S) is an important signaling molecule in colorectal cancer (CRC). It is
produced in the colon by the catalytic synthesis of the colonocytes' enzymatic systems and …

Biogenesis of reactive sulfur species for signaling by hydrogen sulfide oxidation pathways

TV Mishanina, M Libiad, R Banerjee - Nature chemical biology, 2015 - nature.com
The chemical species involved in H2S signaling remain elusive despite the profound and
pleiotropic physiological effects elicited by this molecule. The dominant candidate …

Microbiota metabolites in health and disease

JL McCarville, GY Chen, VD Cuevas… - Annual review of …, 2020 - annualreviews.org
Metabolism is one of the strongest drivers of interkingdom interactions—including those
between microorganisms and their multicellular hosts. Traditionally thought to fuel energy …

H2S signalling through protein sulfhydration and beyond

BD Paul, SH Snyder - Nature reviews Molecular cell biology, 2012 - nature.com
Hydrogen sulfide (H2S) has recently emerged as a mammalian gaseous messenger
molecule, akin to nitric oxide and carbon monoxide. H2S is predominantly formed from Cys …

Reaction of Hydrogen Sulfide with Disulfide and Sulfenic Acid to Form the Strongly Nucleophilic Persulfide*♦

E Cuevasanta, M Lange, J Bonanata, EL Coitiño… - Journal of Biological …, 2015 - ASBMB
Hydrogen sulfide (H 2 S) is increasingly recognized to modulate physiological processes in
mammals through mechanisms that are currently under scrutiny. H 2 S is not able to react …

Redox biochemistry of hydrogen sulfide

O Kabil, R Banerjee - Journal of Biological Chemistry, 2010 - ASBMB
H 2 S, the most recently discovered gasotransmitter, might in fact be the evolutionary
matriarch of this family, being both ancient and highly reduced. Disruption of γ-cystathionase …