Nrf2: redox and metabolic regulator of stem cell state and function
X Dai, X Yan, KA Wintergerst, L Cai, BB Keller… - Trends in Molecular …, 2020 - cell.com
Nuclear factor erythroid 2-related factor 2 (Nrf2) is ubiquitously expressed in most eukaryotic
cells and functions to induce a broad range of cellular defenses against exogenous and …
cells and functions to induce a broad range of cellular defenses against exogenous and …
Radiation‐induced normal tissue damage: oxidative stress and epigenetic mechanisms
J Wei, B Wang, H Wang, L Meng… - Oxidative medicine …, 2019 - Wiley Online Library
Radiotherapy (RT) is currently one of the leading treatments for various cancers; however, it
may cause damage to healthy tissue, with both short‐term and long‐term side effects …
may cause damage to healthy tissue, with both short‐term and long‐term side effects …
[HTML][HTML] Isolation and analysis methods of extracellular vesicles (EVs)
Extracellular vesicles (EVs) have been recognized as an evolving biomarker within the
liquid biopsy family. While carrying both host cell proteins and different types of RNAs, EVs …
liquid biopsy family. While carrying both host cell proteins and different types of RNAs, EVs …
Radioprotection and radiomitigation: from the bench to clinical practice
The development of protective agents against harmful radiations has been a subject of
investigation for decades. However, effective (ideal) radioprotectors and radiomitigators …
investigation for decades. However, effective (ideal) radioprotectors and radiomitigators …
Astaxanthin attenuates total body irradiation-induced hematopoietic system injury in mice via inhibition of oxidative stress and apoptosis
XL Xue, XD Han, Y Li, XF Chu, WM Miao… - Stem Cell Research & …, 2017 - Springer
Background The hematopoietic system is especially sensitive to total body irradiation (TBI),
and myelosuppression is one of the major effects of TBI. Astaxanthin (ATX) is a powerful …
and myelosuppression is one of the major effects of TBI. Astaxanthin (ATX) is a powerful …
[HTML][HTML] Long and short non-coding RNA and radiation response: a review
JM May, M Bylicky, S Chopra, CN Coleman… - Translational …, 2021 - Elsevier
Once thought of as arising from “junk DNA,” non-coding RNAs (ncRNAs) have emerged as
key molecules in cellular processes and response to stress. From diseases such as cancer …
key molecules in cellular processes and response to stress. From diseases such as cancer …
Use of biomarkers for assessing radiation injury and efficacy of countermeasures
Several candidate drugs for acute radiation syndrome (ARS) have been identified that have
low toxicity and significant radioprotective and radiomitigative efficacy. Inasmuch as …
low toxicity and significant radioprotective and radiomitigative efficacy. Inasmuch as …
Evolutionarily conserved serum microRNAs predict radiation-induced fatality in nonhuman primates
Effective planning for the medical response to a radiological or nuclear accident is complex.
Because of limited resources for medical countermeasures, the key would be to accurately …
Because of limited resources for medical countermeasures, the key would be to accurately …
MicroRNA: a novel implication for damage and protection against ionizing radiation
Y Chen, J Cui, Y Gong, S Wei, Y Wei, L Yi - Environmental Science and …, 2021 - Springer
Ionizing radiation (IR) is a form of high energy. It poses a serious threat to organisms, but
radiotherapy is a key therapeutic strategy for various cancers. It is significant to reduce …
radiotherapy is a key therapeutic strategy for various cancers. It is significant to reduce …