Abstract Changes in epigenetic marks such as DNA methylation and histone acetylation are
associated with a broad range of disease traits, including cancer, asthma, metabolic …

Twin studies are powerful tools to discriminate whether a complex disease is due to genetic
or environmental factors. High concordance rates among monozygotic (MZ) twins support …

Background Systemic lupus erythematosus (SLE) is a multisystemic, chronic inflammatory
disease characterized by destructive systemic organ involvement, which could cause the …

Introduction B cell depletion therapy is efficacious in rheumatoid arthritis (RA) patients failing
on tumor necrosis factor (TNF) blocking agents. However, approximately 40% to 50% of …

Autoimmunity and chronic inflammation recognize numerous shared factors and, as a result,
the resulting diseases frequently coexist in the same patients or respond to the same …

Importance To date, there is no diagnostic test for Kawasaki disease (KD). Diagnosis is
based on clinical features shared with other febrile conditions, frequently resulting in …

Common inflammatome gene signatures as well as disease‐specific signatures were
identified by analyzing 12 expression profiling data sets derived from 9 different tissues …

Objective The aim of this prospective multicenter study was to identify biomarkers that can
be used to predict therapeutic responses to tocilizumab in patients with rheumatoid arthritis …

Background Systemic lupus erythematosus (SLE) is an autoimmune illness caused by a
malfunctioning immunomodulatory system. China has the second highest prevalence of SLE …

Objective To identify shared and differential molecular pathways involved in the
pathogenesis of atherosclerosis (AT) and cardiovascular disease (CVD) in systemic lupus …