The CCL2-CCR2 axis is one of the major chemokine signaling pathways that has received
special attention because of its function in the development and progression of …

Cardiovascular diseases (CVDs) have become a serious threat to human life and health.
Though many drugs acting via different mechanism of action are available in the market as …

Cardiovascular diseases (CVD) are major causes of death worldwide. Recently, new roles
for intestinal microbiota in pathology and treatment of CVD have been proposed. Butyrate, a …

Atherosclerosis underlies the predominant number of cardiovascular diseases and remains
a leading cause of morbidity and mortality worldwide. The development, progression and …

Highlights•MicroRNAs play a major role in cancer.•Several clinical trials with microRNA are
reported for cancer treatment.•Delivery of microRNA encounters several challenges.•We …

Aging-induced alternations of vasculature structures, phenotypes, and functions are key in
the occurrence and development of vascular aging-related diseases. Multiple molecular and …

The heparins, well-known for their anticoagulant properties, may also have anti-
inflammatory effects that could contribute to their effectiveness in the treatment of venous …

Atherosclerosis is the build-up of fatty deposits in the arteries. Atherosclerosis is the main
underlying cause of cardiovascular diseases and the leading cause of global morbidity and …

The surface of endothelial cells is covered with cell adhesion molecules, including E‐
selectin, intercellula adhesion molecule 1 (ICAM‐1), and vascular cell adhesion molecule 1 …

Atherosclerosis represents a significant cause of morbidity and mortality in both the
developed and developing countries. Animal models of atherosclerosis have served as …