[HTML][HTML] Review of hybrid PLGA nanoparticles: Future of smart drug delivery and theranostics medicine

J Ghitman, EI Biru, R Stan, H Iovu - Materials & Design, 2020 - Elsevier
The concept of PLGA-lipid hybrid nanoparticles arose as a motivation for developing drug
delivery systems with versatile physical and chemical properties, unequivocal therapeutic …

Chitosan on the surface of nanoparticles for enhanced drug delivery: A comprehensive review

MH Elkomy, AA Ali, HM Eid - Journal of Controlled Release, 2022 - Elsevier
The ability of chitosan (CTS) to promote mucoadhesion, trigger positive/negative surface
interactions, and open tight junctions has inspired researchers to coat lipid-based and …

Chitosan as a coating material for nanoparticles intended for biomedical applications

LA Frank, GR Onzi, AS Morawski, AR Pohlmann… - Reactive and Functional …, 2020 - Elsevier
This review provides a comprehensive and updated overview of the state of the art related to
the biomedical applications of nanoparticles coated with chitosan. Discussions were based …

Nanoparticle-mediated pulmonary drug delivery: a review

M Paranjpe, CC Müller-Goymann - International journal of molecular …, 2014 - mdpi.com
Colloidal drug delivery systems have been extensively investigated as drug carriers for the
application of different drugs via different routes of administration. Systems, such as solid …

Delivery strategies for sustained drug release in the lungs

C Loira-Pastoriza, J Todoroff, R Vanbever - Advanced drug delivery reviews, 2014 - Elsevier
Drug delivery to the lungs by inhalation offers a targeted drug therapy for respiratory
diseases. However, the therapeutic efficacy of inhaled drugs is limited by their rapid …

Chitosan nanoparticle-based system: A new insight into the promising controlled release system for lung cancer treatment

C Yee Kuen, MJ Masarudin - Molecules, 2022 - mdpi.com
Lung cancer has been recognized as one of the most often diagnosed and perhaps most
lethal cancer diseases worldwide. Conventional chemotherapy for lung cancer-related …

Recent advances in chitosan-based nanoparticulate pulmonary drug delivery

N Islam, V Ferro - Nanoscale, 2016 - pubs.rsc.org
The advent of biodegradable polymer-encapsulated drug nanoparticles has made the
pulmonary route of administration an exciting area of drug delivery research. Chitosan, a …

Recent advances in protein and peptide drug delivery: a special emphasis on polymeric nanoparticles

A Patel, M Patel, X Yang, AK Mitra - Protein and peptide letters, 2014 - ingentaconnect.com
Proteins and peptides are widely indicated in many diseased states. Parenteral route is the
most commonly em-ployed method of administration for therapeutic proteins and peptides …

Barrier or carrier? Pulmonary surfactant and drug delivery

A Hidalgo, A Cruz, J Pérez-Gil - European Journal of Pharmaceutics and …, 2015 - Elsevier
To consider the lung as a target for drug delivery and to optimise strategies directed at the
pulmonary route, it is essential to consider the role of pulmonary surfactant, a thin lipid …

Poly(lactide-co-glycolide) Nanoparticles for Prolonged Therapeutic Efficacy of Esculentin-1a-Derived Antimicrobial Peptides against Pseudomonas aeruginosa Lung …

B Casciaro, I d'Angelo, X Zhang, MR Loffredo… - …, 2019 - ACS Publications
Due to their excellent in vitro activity against multidrug resistant bacteria, antimicrobial
peptides (AMPs) hold promise for treatment of Pseudomonas aeruginosa lung infections in …