With the rising prevalence of autoimmune diseases, the role of the environment, specifically
the gut microbiota, in disease development has grown to be a major area of study. Recent …

The intestinal epithelial lining, together with factors secreted from it, forms a barrier that
separates the host from the environment. In pathologic conditions, the permeability of the …

Autoimmune diseases are a series of diseases involving multiple tissues and organs,
characterized by the over production of abnormal multiple antibodies. Although most studies …

Unresolved low grade systemic inflammation represents the underlying pathological
mechanism driving immune and metabolic pathways involved in autoimmune diseases …

Autoimmune diseases are immune disorders characterized by T cell hyperactivity and B cell
overstimulation leading to overproduction of autoantibodies. Although the pathogenesis of …

Damage to the tissue and the ruining of functions characterize autoimmune syndromes. This
review centers around leaky gut syndromes and how they stimulate autoimmune …

Lupus nephritis remains one of the most severe manifestations of systemic lupus
erythematosus associated with considerable morbidity and mortality. A better understanding …

Systemic lupus erythematosus (SLE) is a multi-system autoimmune disease. Despite years
of study, the etiology of SLE is still unclear. Both genetic and environmental factors have …

The mechanisms leading to autoimmune diseases remain largely unknown despite
numerous lines of experimental inquiry and epidemiological evidence. The growing number …

B cells secreting IL-10 functionally are recognized as functional regulatory B (Breg) cells;
however, direct evidence concerning the phenotype, regulation, and functional and clinical …