Cyclopropanes are of great synthetic value in heterocyclic chemistry due to their highly
reactive nature. They are widely employed to synthesize various biologically active organic …

Spiro compounds being multi-cyclic systems linked by a single atom, have distinct three
dimensionalities, and prominently hold a position of interest in the fields of synthetic and …

An unprecedented approach to synthesize spirobutyrolactone para-dienones from para-
quinone methides and bromo-Meldrum's acids has been developed. A series of spatially …

A highly efficient domino aza-MIRC (Michael Induced Ring Closure) reaction between
barbiturate-derived alkenes and N-alkoxy α-haloamides has been achieved in moderate to …

The stereoselective sequential spirocyclopropanation/Cloke–Wilson rearrangement
reactions have been developed to synthesize γ-butyrolactones using alkylidene Meldrum's …

Pyrimidine annulated five‐membered heterocyclic scaffolds containing oxygen as
furopyrimidine, particularly furo [2, 3‐d] pyrimidine derivatives are an important class of …

Base-mediated stereospecific tandem reactions using para-quinone methides and carbene-
like benzyl chlorides are developed. DBU-mediated 1, 6-addition/cyclization/isomerization …

A diastereoselective synthesis of biologically interesting spirobarbiturates has been
achieved via [3+ 2] cycloaddition of alloxan-derived azomethine ylides to 3-R-1, 2 …

Abstract The AlCl3 promoted stereospecific Cloke‐Wilson rearrangement of
spirocyclopropyl barbiturates has been developed. The reactions were carried out efficiently …

Pyrimidine‐based derivatives have attracted a lot of interest in heterocyclic chemistry due to
its versatile structure and diverse biological activities. This study provides a comprehensive …