Multidrug efflux transporter ABCG2: expression and regulation
The adenosine triphosphate (ATP)-binding cassette efflux transporter G2 (ABCG2) was
originally discovered in a multidrug-resistant breast cancer cell line. Studies in the past have …
originally discovered in a multidrug-resistant breast cancer cell line. Studies in the past have …
Reporters of cancer stem cells as a tool for drug discovery
A Mohan, R Raj R, G Mohan, P KP… - Frontiers in …, 2021 - frontiersin.org
In view of the importance of cancer stem cells (CSCs) in chemoresistance, metastasis and
recurrence, the biology of CSCs were explored in detail. Based on that, several modalities …
recurrence, the biology of CSCs were explored in detail. Based on that, several modalities …
Quinacrine and curcumin synergistically increased the breast cancer stem cells death by inhibiting ABCG2 and modulating DNA damage repair pathway
D Nayak, N Tripathi, D Kathuria, S Siddharth… - The international journal …, 2020 - Elsevier
Cancer stem cell like cells (CSCs) present a challenge in the management of cancers due to
their involvement in the development of resistance against various chemotherapeutic …
their involvement in the development of resistance against various chemotherapeutic …
Pharmacodynamic mechanisms of anti-inflammatory drugs on the chemosensitization of multidrug-resistant cancers and the pharmacogenetics effectiveness
N Gholamian Dehkordi, SA Mirzaei, F Elahian - Inflammopharmacology, 2021 - Springer
Drug resistance as a remarkable issue in cancer treatment is associated with inflammation
which occurs through complex chemical reactions in the tumor microenvironment. Recent …
which occurs through complex chemical reactions in the tumor microenvironment. Recent …
Zebrafish (Danio rerio) ecotoxicological ABCB4, ABCC1 and ABCG2a gene promoters depict spatiotemporal xenobiotic multidrug resistance properties against …
Marine organisms are naturally equipped with multixenobiotic resistance mechanisms that
are often governed by ATP-binding cassette (ABC) transporter family members. Previous …
are often governed by ATP-binding cassette (ABC) transporter family members. Previous …
Comprehensive breast cancer risk analysis with whole exome sequencing and the prevalence of BRCA1 and ABCG2 mutations and oncogenic HPV
Breast cancer is the most prevalent cancer and also the leading cause of cancer death in
women worldwide. A comprehensive understanding of breast cancer risk factors and their …
women worldwide. A comprehensive understanding of breast cancer risk factors and their …
Specyficzność substratowa, aktywność i lokalizacja subkomórkowa ludzkiego białka oporności wielolekowej ABCG2
M Studzian - 2023 - dspace.uni.lodz.pl
Białko ABCG2 u człowieka funkcjonuje jako transporter wielu substancji o znaczeniu
fizjologicznym–metabolitów, składników pożywienia, leków. Celem niniejszej pracy było …
fizjologicznym–metabolitów, składników pożywienia, leków. Celem niniejszej pracy było …
Role of transportome in the pharmacogenomics of hepatocellular carcinoma and hepatobiliary cancer
M Alonso-Peña, RA Espinosa-Escudero… - …, 2019 - Taylor & Francis
An important factor determining the pharmacological response to antitumor drugs is their
concentrations in cancer cells, which accounts for the net interaction with their intracellular …
concentrations in cancer cells, which accounts for the net interaction with their intracellular …