The rapid emergence and spread of drug-resistant bacteria, as one of the most pressing
public health threats, are declining our arsenal of available antimicrobial drugs. Advanced …

The precorneal tear film is a complex mixture of proteins, lipids, metabolites, and electrolytes
with different structures and functionalities. Sustainable production of each tear component …

Infectious keratitis caused by bacterial biofilms is one of the main causes of corneal
blindness, presenting a serious threat to public health. In this study, matrix metalloproteinase …

Contact lenses in the future will likely have functions other than correction of refractive error.
Lenses designed to control the development of myopia are already commercially available …

Background Dry eye disease (DED) is among the most prevalent ophthalmic conditions but
is often underdiagnosed and mistreated. Antibiotics are regularly used to treat DED caused …

The damage of corneal epithelium may lead to the formation of irreversible corneal opacities
and even blindness. The migration rate of corneal epithelial cells directly affects corneal …

Peripheral ulcerative keratitis (PUK) is a rare but serious ocular condition that is an important
clinical entity due to its ophthalmological and systemic implications. It is characterized by …

During infectious keratitis, the production of collagenolytic and inflammatory substances,
along with increased corneal matrix metalloproteinase (MMP) activity, induces the …

Bacterial infection is a series of pathological changes caused by bacteria invading the host
and interacting with the body. Nowadays, bacterial infection remains a major public health …

Alpha‐lipoic acid (ALA) is a naturally occurring dithiol micronutrient which acts as a cofactor
for mitochondrial enzyme activity. Due to its potential antioxidant activity, it is considered as …