Over the past decade, with the development of high-throughput single-cell sequencing
technology, single-cell omics has been emerged as a powerful tool to understand the …

Macrophages are vital tissue components involved in organogenesis, maintaining
homeostasis, and responses to disease. Mouse models have significantly improved our …

The rapid development of high-throughput single-cell RNA sequencing technology offers a
good opportunity to dissect cell heterogeneity of animals. A large number of organism-wide …

Despite recent advances in single-cell genomics, the lack of maps for single-cell candidate
cis-regulatory elements (cCREs) in non-mammal species has limited our exploration of …

Monkey disease models, which are comparable to humans in terms of genetic, anatomical,
and physiological characteristics, are important for understanding disease mechanisms and …

Mouse lemurs are the smallest, fastest reproducing, and among the most abundant
primates, and an emerging model organism for primate biology, behavior, health and …

Neutrophils are important immune cells act as the body's first line of defense against
infection and respond to diverse inflammatory cues. Many studies have demonstrated that …

Recent advancements in single‐cell technologies have led to rapid developments in the
construction of cell atlases. These atlases have the potential to provide detailed information …

Single-cell omics technologies provide an unprecedented opportunity to decipher molecular
mechanisms underlying various biological processes in a cellular heterogeneity manner …

To solve the clinical transformation dilemma of lamin A/C (LMNA)-mutated dilated
cardiomyopathy (LMD), we developed an LMNA-mutated primate model based on the …