[HTML][HTML] Single-cell omics: A new direction for functional genetic research in human diseases and animal models
S Kong, R Li, Y Tian, Y Zhang, Y Lu, Q Ou, P Gao… - Frontiers in …, 2023 - frontiersin.org
Over the past decade, with the development of high-throughput single-cell sequencing
technology, single-cell omics has been emerged as a powerful tool to understand the …
technology, single-cell omics has been emerged as a powerful tool to understand the …
[HTML][HTML] Cell landscape of larval and adult Xenopus laevis at single-cell resolution
Y Liao, L Ma, Q Guo, WE, X Fang, L Yang… - nature …, 2022 - nature.com
The rapid development of high-throughput single-cell RNA sequencing technology offers a
good opportunity to dissect cell heterogeneity of animals. A large number of organism-wide …
good opportunity to dissect cell heterogeneity of animals. A large number of organism-wide …
Construction of single-cell cross-species chromatin accessibility landscapes with combinatorial-hybridization-based ATAC-seq
G Zhang, Y Fu, L Yang, F Ye, P Zhang, S Zhang, L Ma… - Developmental Cell, 2024 - cell.com
Despite recent advances in single-cell genomics, the lack of maps for single-cell candidate
cis-regulatory elements (cCREs) in non-mammal species has limited our exploration of …
cis-regulatory elements (cCREs) in non-mammal species has limited our exploration of …
[HTML][HTML] Single-cell transcriptomic characterization reveals the landscape of airway remodeling and inflammation in a cynomolgus monkey model of asthma
Y Wang, X Dong, C Pan, C Zhu, H Qi, Y Wang… - Frontiers in …, 2022 - frontiersin.org
Monkey disease models, which are comparable to humans in terms of genetic, anatomical,
and physiological characteristics, are important for understanding disease mechanisms and …
and physiological characteristics, are important for understanding disease mechanisms and …
Tabula Microcebus: A transcriptomic cell atlas of mouse lemur, an emerging primate model organism
Tabula Microcebus Consortium, C Ezran, S Liu… - BioRxiv, 2021 - biorxiv.org
Mouse lemurs are the smallest, fastest reproducing, and among the most abundant
primates, and an emerging model organism for primate biology, behavior, health and …
primates, and an emerging model organism for primate biology, behavior, health and …
The double‐edged role of neutrophil heterogeneity in inflammatory diseases and cancers
W Zhou, X Cao, Q Xu, J Qu, Y Sun - MedComm, 2023 - Wiley Online Library
Neutrophils are important immune cells act as the body's first line of defense against
infection and respond to diverse inflammatory cues. Many studies have demonstrated that …
infection and respond to diverse inflammatory cues. Many studies have demonstrated that …
Mapping Cell Atlases at the Single‐Cell Level
Recent advancements in single‐cell technologies have led to rapid developments in the
construction of cell atlases. These atlases have the potential to provide detailed information …
construction of cell atlases. These atlases have the potential to provide detailed information …
[HTML][HTML] Exploring long non-coding RNA networks from single cell omics data
X Zhao, Y Lan, D Chen - Computational and Structural Biotechnology …, 2022 - Elsevier
Single-cell omics technologies provide an unprecedented opportunity to decipher molecular
mechanisms underlying various biological processes in a cellular heterogeneity manner …
mechanisms underlying various biological processes in a cellular heterogeneity manner …
Primate model carrying LMNA mutation develops dilated cardiomyopathy
X Luo, H Jia, F Wang, H Mo, Y Kang, N Zhang… - Basic to Translational …, 2024 - jacc.org
To solve the clinical transformation dilemma of lamin A/C (LMNA)-mutated dilated
cardiomyopathy (LMD), we developed an LMNA-mutated primate model based on the …
cardiomyopathy (LMD), we developed an LMNA-mutated primate model based on the …