Extrachromosomal circular DNA drives oncogenic genome remodeling in neuroblastoma
Extrachromosomal circularization of DNA is an important genomic feature in cancer.
However, the structure, composition and genome-wide frequency of extrachromosomal …
However, the structure, composition and genome-wide frequency of extrachromosomal …
Purification, full-length sequencing and genomic origin mapping of eccDNA
Extrachromosomal circular DNA (eccDNA) was discovered more than half a century ago.
However, its biogenesis and function have just begun to be elucidated. One hurdle that has …
However, its biogenesis and function have just begun to be elucidated. One hurdle that has …
Intratumoral heterogeneity and clonal evolution induced by HPV integration
The human papillomavirus (HPV) genome is integrated into host DNA in most HPV-positive
cancers, but the consequences for chromosomal integrity are unknown. Continuous long …
cancers, but the consequences for chromosomal integrity are unknown. Continuous long …
Long-read sequencing of diagnosis and post-therapy medulloblastoma reveals complex rearrangement patterns and epigenetic signatures
Cancer genomes harbor a broad spectrum of structural variants (SVs) driving tumorigenesis,
a relevant subset of which escape discovery using short-read sequencing. We employed …
a relevant subset of which escape discovery using short-read sequencing. We employed …
Detection and validation of circular DNA fragments using Nanopore sequencing
AI Tüns, T Hartmann, S Magin, RC González… - Frontiers in …, 2022 - frontiersin.org
Occurrence of extra-chromosomal circular DNA is a phenomenon frequently observed in
tumor cells, and the presence of such DNA has been recognized as a marker of adverse …
tumor cells, and the presence of such DNA has been recognized as a marker of adverse …
A comprehensive study of extrachromosomal circular DNA in pancreatic ductal adenocarcinoma
D Schreyer - 2024 - theses.gla.ac.uk
Introduction: Extrachromosomal circular DNAs (eccDNA) vary in sizes and drive many
aspects of tumour biology, including drug resistance and oncogene amplification. However …
aspects of tumour biology, including drug resistance and oncogene amplification. However …
[PDF][PDF] Mechanism Investigation and Efficiency Enhancement of Nucleic Acid Extraction by Using Plant Fiber-Based Adsorbents
X Ye - 2023 - scholars.hkbu.edu.hk
Nucleic acid extraction is an essential part during biological analysis. Some studies show
DNA adsorbability of filter paper that is composed plant fiber-based adsorbent. However, the …
DNA adsorbability of filter paper that is composed plant fiber-based adsorbent. However, the …