Progress report on new antiepileptic drugs: a summary of the Twelfth Eilat Conference (EILAT XII)
M Bialer, SI Johannessen, RH Levy, E Perucca… - Epilepsy research, 2015 - Elsevier
Summary The Twelfth Eilat Conference on New Antiepileptic Drugs (AEDs)–EILAT XII, took
place in Madrid, Spain from August 31st to September 3rd 2014. About 130 basic scientists …
place in Madrid, Spain from August 31st to September 3rd 2014. About 130 basic scientists …
Insights into structural modifications of valproic acid and their pharmacological profile
Valproic acid (VPA) is a well-established anticonvulsant drug discovered serendipitously
and marketed for the treatment of epilepsy, migraine, bipolar disorder and neuropathic pain …
and marketed for the treatment of epilepsy, migraine, bipolar disorder and neuropathic pain …
Progress report on new antiepileptic drugs: a summary of the Thirteenth Eilat Conference on New Antiepileptic Drugs and Devices (EILAT XIII)
M Bialer, SI Johannessen, RH Levy, E Perucca… - …, 2017 - Wiley Online Library
Summary The Thirteenth Eilat Conference on New Antiepileptic Drugs and Devices (EILAT
XIII) took place in Madrid, Spain, on June 26–29, 2016, and was attended by> 200 …
XIII) took place in Madrid, Spain, on June 26–29, 2016, and was attended by> 200 …
Progress report on new antiepileptic drugs: A summary of the Fifteenth Eilat Conference on New Antiepileptic Drugs and Devices (EILAT XV). I. Drugs in preclinical …
M Bialer, SI Johannessen, MJ Koepp, RH Levy… - …, 2020 - Wiley Online Library
Abstract Since 1992, the Eilat Conferences have provided a forum for all stakeholders in the
epilepsy community to appraise the latest data on new antiepileptic drugs and emergency …
epilepsy community to appraise the latest data on new antiepileptic drugs and emergency …
Post-treatment with the GLP-1 analogue liraglutide alleviate chronic inflammation and mitochondrial stress induced by Status epilepticus
RF Wang, GF Xue, C Hölscher, MJ Tian, P Feng… - Epilepsy Research, 2018 - Elsevier
Abstract Glucagon-like peptide-1 (GLP-1) is a growth factor that has neuroprotective and anti-
inflammatory properties. The protease resistant GLP-1 analogue liraglutide has been shown …
inflammatory properties. The protease resistant GLP-1 analogue liraglutide has been shown …
A rodent model of human organophosphate exposure producing status epilepticus and neuropathology
W Pouliot, SL Bealer, B Roach, FE Dudek - Neurotoxicology, 2016 - Elsevier
Exposure to organophosphates (OPs) often results in seizures and/or status epilepticus (SE)
that produce neural damage within the central nervous system (CNS). Early control of SE is …
that produce neural damage within the central nervous system (CNS). Early control of SE is …
Moving beyond sodium valproate: choosing the right anti-epileptic drug in children
G Balagura, G Iapadre, A Verrotti… - Expert opinion on …, 2019 - Taylor & Francis
Introduction: Sodium valproate is a widely used anti-epileptic drug with a broad spectrum of
activity and mechanism of action. It has consequently been the first-line drug for most …
activity and mechanism of action. It has consequently been the first-line drug for most …
Long-term continuous EEG monitoring in small rodent models of human disease using the epoch wireless transmitter system
A Zayachkivsky, MJ Lehmkuhle… - Journal of visualized …, 2015 - pmc.ncbi.nlm.nih.gov
Many progressive neurologic diseases in humans, such as epilepsy, require pre-clinical
animal models that slowly develop the disease in order to test interventions at various …
animal models that slowly develop the disease in order to test interventions at various …
Mitochondrial liver toxicity of valproic acid and its acid derivatives is related to inhibition of α-lipoamide dehydrogenase
AP Kudin, H Mawasi, A Eisenkraft, CE Elger… - International Journal of …, 2017 - mdpi.com
The liver toxicity of valproic acid (VPA) is an established side effect of this widely used
antiepileptic drug, which is extremely problematic for patients with metabolic epilepsy and …
antiepileptic drug, which is extremely problematic for patients with metabolic epilepsy and …
Disease modification in epilepsy: from animal models to clinical applications
Several relevant animal models of epileptogenesis and biomarkers have emerged for
evaluating the antiepileptogenic potential of an investigational drug. Although several …
evaluating the antiepileptogenic potential of an investigational drug. Although several …