Evidence-based clinical practice guidelines for inflammatory bowel disease 2020

H Nakase, M Uchino, S Shinzaki, M Matsuura… - Journal of …, 2021 - Springer
Inflammatory bowel disease (IBD) is a general term for chronic or remitting/relapsing
inflammatory diseases of the intestinal tract and generally refers to ulcerative colitis (UC) …

British Society of Gastroenterology consensus guidelines on the management of inflammatory bowel disease in adults

CA Lamb, NA Kennedy, T Raine, PA Hendy, PJ Smith… - Gut, 2019 - gut.bmj.com
Ulcerative colitis and Crohn's disease are the principal forms of inflammatory bowel disease.
Both represent chronic inflammation of the gastrointestinal tract, which displays …

Effectiveness and safety of ustekinumab in inflammatory bowel disease: a systematic review and meta-analysis

S Honap, S Meade, H Ibraheim, PM Irving… - Digestive Diseases and …, 2022 - Springer
Introduction Ustekinumab, an interleukin-12 and interleukin-23 antagonist, is licensed for the
treatment of Crohn's disease (CD) and ulcerative colitis (UC) after the phase III trial …

Safety of ustekinumab or vedolizumab in pregnant inflammatory bowel disease patients: a multicentre cohort study

P Wils, P Seksik, C Stefanescu… - Alimentary …, 2021 - Wiley Online Library
Background The prevalence of inflammatory bowel diseases (IBD) is high in women of
childbearing age. Achieving clinical remission from conception to delivery using current …

Safety of new biologics (vedolizumab and ustekinumab) and small molecules (tofacitinib) during pregnancy: a review

JP Gisbert, M Chaparro - Drugs, 2020 - Springer
Two new biological drugs (vedolizumab and ustekinumab) and one small molecule
(tofacitinib) have been recently approved for the treatment of inflammatory bowel disease …

Effectiveness and safety of Ustekinumab for Crohn's disease; systematic review and pooled analysis of real-world evidence

T Engel, DE Yung, C Ma, B Pariente, P WIls… - Digestive and Liver …, 2019 - Elsevier
Background Ustekinumab [UST] is effective in Crohn's disease (CD) in the UNITI studies.
Several real-world experience (RWE) studies with UST have been published to date. Our …

Use of medications during pregnancy and breastfeeding for Crohn's disease and ulcerative colitis

R Laube, S Paramsothy, RW Leong - Expert Opinion on Drug …, 2021 - Taylor & Francis
Introduction: The peak age of diagnosis of inflammatory bowel disease (IBD) occurs during
childbearing years, therefore management of IBD during pregnancy is a frequent …

Biologics during pregnancy and breastfeeding among women with rheumatic diseases: safety clinical evidence on the road

A Beltagy, A Aghamajidi, L Trespidi, W Ossola… - Frontiers in …, 2021 - frontiersin.org
Females are generally more affected by autoimmune diseases, a fact that underlines the
relationship with pregnancy and the safety of anti-rheumatic drugs in pregnancy and …

Drug levels in the maternal serum, cord blood and breast milk of a ustekinumab-treated patient with Crohn's disease

E Klenske, L Osaba, D Nagore, T Rath… - Journal of Crohn's …, 2019 - academic.oup.com
Ustekinumab [UST] therapy during pregnancy has not yet been extensively evaluated in
patients with Crohn's disease. Here, we present the case of a 24-year-old woman with …

The use of biologics and small molecules in pregnant patients with rheumatic diseases

M Gerosa, LM Argolini, C Artusi… - Expert review of clinical …, 2018 - Taylor & Francis
Introduction: Biological agents have radically changed the prognosis of rheumatic patients.
Current evidence demonstrates that tight disease control during pregnancy is mandatory to …